Selection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep)

Asma Guellouz; Marie Valerio-Lepiniec; Agathe Urvoas; Anne Chevrel; Marc Graille; Zaineb Fourati-Kammoun; Michel Desmadril; Herman van Tilbeurgh; Philippe Minard

doi:10.1371/journal.pone.0071512

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Peer-reviewed

Research Article

Selection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep)

Asma Guellouz ,

Contributed equally to this work with: Asma Guellouz, Marie Valerio-Lepiniec, Agathe Urvoas

Affiliations Institut de Biochimie et Biophysique Moléculaire et Cellulaire, Université Paris-Sud, Orsay, France, Unité Mixte de Recherche 8619, Centre National de Recherche Scientifique, Orsay, France
⨯
Marie Valerio-Lepiniec ,

Contributed equally to this work with: Asma Guellouz, Marie Valerio-Lepiniec, Agathe Urvoas

Affiliations Institut de Biochimie et Biophysique Moléculaire et Cellulaire, Université Paris-Sud, Orsay, France, Unité Mixte de Recherche 8619, Centre National de Recherche Scientifique, Orsay, France
⨯
Agathe Urvoas ,

Contributed equally to this work with: Asma Guellouz, Marie Valerio-Lepiniec, Agathe Urvoas

Affiliations Institut de Biochimie et Biophysique Moléculaire et Cellulaire, Université Paris-Sud, Orsay, France, Unité Mixte de Recherche 8619, Centre National de Recherche Scientifique, Orsay, France
⨯
Anne Chevrel,

Affiliations Institut de Biochimie et Biophysique Moléculaire et Cellulaire, Université Paris-Sud, Orsay, France, Unité Mixte de Recherche 8619, Centre National de Recherche Scientifique, Orsay, France
⨯
Marc Graille,

Current address: Laboratoire de Biochimie, Unité Mixte de Recherche 7654, Centre National de Recherche Scientifique, Ecole Polytechnique, Palaiseau, France

Affiliations Institut de Biochimie et Biophysique Moléculaire et Cellulaire, Université Paris-Sud, Orsay, France, Unité Mixte de Recherche 8619, Centre National de Recherche Scientifique, Orsay, France
⨯
Zaineb Fourati-Kammoun,

Current address: Laboratoire de Biochimie, Unité Mixte de Recherche 7654, Centre National de Recherche Scientifique, Ecole Polytechnique, Palaiseau, France

Affiliations Institut de Biochimie et Biophysique Moléculaire et Cellulaire, Université Paris-Sud, Orsay, France, Unité Mixte de Recherche 8619, Centre National de Recherche Scientifique, Orsay, France
⨯
Michel Desmadril,

Affiliations Institut de Biochimie et Biophysique Moléculaire et Cellulaire, Université Paris-Sud, Orsay, France, Unité Mixte de Recherche 8619, Centre National de Recherche Scientifique, Orsay, France
⨯
Herman van Tilbeurgh,

Affiliations Institut de Biochimie et Biophysique Moléculaire et Cellulaire, Université Paris-Sud, Orsay, France, Unité Mixte de Recherche 8619, Centre National de Recherche Scientifique, Orsay, France
⨯
Philippe Minard

* E-mail: philippe.minard@u-psud.fr

Affiliations Institut de Biochimie et Biophysique Moléculaire et Cellulaire, Université Paris-Sud, Orsay, France, Unité Mixte de Recherche 8619, Centre National de Recherche Scientifique, Orsay, France
⨯

Selection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep)

Asma Guellouz,
Marie Valerio-Lepiniec,
Agathe Urvoas,
Anne Chevrel,
Marc Graille,
Zaineb Fourati-Kammoun,
Michel Desmadril,
Herman van Tilbeurgh,
Philippe Minard

Published: August 27, 2013
https://doi.org/10.1371/journal.pone.0071512

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