The Antihelmintic Drug Pyrvinium Pamoate Targets Aggressive Breast Cancer

Wei Xu; Lara Lacerda; Bisrat G. Debeb; Rachel L. Atkinson; Travis N. Solley; Li Li; Darren Orton; John S. McMurray; Brian I. Hang; Ethan Lee; Ann H. Klopp; Naoto T. Ueno; James M. Reuben; Savitri Krishnamurthy; Wendy A. Woodward

doi:10.1371/journal.pone.0071508

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Open Access

Peer-reviewed

Research Article

The Antihelmintic Drug Pyrvinium Pamoate Targets Aggressive Breast Cancer

Wei Xu,

Affiliation Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Lara Lacerda,

Affiliation Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Bisrat G. Debeb,

Affiliation Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Rachel L. Atkinson,

Affiliation Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Travis N. Solley,

Affiliation Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Li Li,

Affiliation Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Darren Orton,

Affiliation StemSynergy Therapeutics, Inc., Lauderdale by the Sea, Florida, United States of America
⨯
John S. McMurray,

Affiliation Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Brian I. Hang,

Affiliation Department of Cell and Developmental Biology, Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯
Ethan Lee,

Affiliation Department of Cell and Developmental Biology, Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯
Ann H. Klopp,

Affiliation Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Naoto T. Ueno,

Affiliation Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
James M. Reuben,

Affiliation Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Savitri Krishnamurthy,

Affiliation Division of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Wendy A. Woodward

* E-mail: wwoodward@mdanderson.org

Affiliation Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯

The Antihelmintic Drug Pyrvinium Pamoate Targets Aggressive Breast Cancer

Wei Xu,
Lara Lacerda,
Bisrat G. Debeb,
Rachel L. Atkinson,
Travis N. Solley,
Li Li,
Darren Orton,
John S. McMurray,
Brian I. Hang,
Ethan Lee

Published: August 27, 2013
https://doi.org/10.1371/journal.pone.0071508

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