RNA-Mediated Gene Silencing of Nicotinamide N-Methyltransferase Is Associated with Decreased Tumorigenicity in Human Oral Carcinoma Cells

Valentina Pozzi; Davide Sartini; Stefano Morganti; Rachela Giuliante; Giulia Di Ruscio; Andrea Santarelli; Romina Rocchetti; Corrado Rubini; Marco Tomasetti; Giovanni Giannatempo; Fiorenza Orlando; Mauro Provinciali; Lorenzo Lo Muzio; Monica Emanuelli

doi:10.1371/journal.pone.0071272

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Open Access

Peer-reviewed

Research Article

RNA-Mediated Gene Silencing of Nicotinamide N-Methyltransferase Is Associated with Decreased Tumorigenicity in Human Oral Carcinoma Cells

Valentina Pozzi,

Affiliation Department of Clinical Sciences, Polytechnic University of Marche, Ancona, Italy
⨯
Davide Sartini,

Affiliation Department of Clinical Sciences, Polytechnic University of Marche, Ancona, Italy
⨯
Stefano Morganti,

Affiliation Department of Clinical Sciences, Polytechnic University of Marche, Ancona, Italy
⨯
Rachela Giuliante,

Affiliation Department of Clinical Sciences, Polytechnic University of Marche, Ancona, Italy
⨯
Giulia Di Ruscio,

Affiliation Department of Clinical Sciences, Polytechnic University of Marche, Ancona, Italy
⨯
Andrea Santarelli,

Affiliations Department of Clinical Sciences, Polytechnic University of Marche, Ancona, Italy, I.R.C.C.S. I.N.R.C.A., Ancona, Italy
⨯
Romina Rocchetti,

Affiliation Department of Biomedical Sciences and Public Health, Polytechnic University of Marche, Ancona, Italy
⨯
Corrado Rubini,

Affiliation Department of Biomedical Sciences and Public Health, Polytechnic University of Marche, Ancona, Italy
⨯
Marco Tomasetti,

Affiliation Department of Molecular and Clinical Sciences, Polytechnic University of Marche, Ancona, Italy
⨯
Giovanni Giannatempo,

Affiliation Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy
⨯
Fiorenza Orlando,

Affiliation Experimental Animal Models for Aging Units, IRCCS-INRCA, Ancona, Italy
⨯
Mauro Provinciali,

Affiliation Advanced Technology Center for Aging Research, Scientific Technological Area, IRCCS-INRCA, Ancona, Italy
⨯
Lorenzo Lo Muzio,

Affiliation Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy
⨯
Monica Emanuelli

* E-mail: m.emanuelli@univpm.it

Affiliation Department of Clinical Sciences, Polytechnic University of Marche, Ancona, Italy
⨯

RNA-Mediated Gene Silencing of Nicotinamide N-Methyltransferase Is Associated with Decreased Tumorigenicity in Human Oral Carcinoma Cells

Valentina Pozzi,
Davide Sartini,
Stefano Morganti,
Rachela Giuliante,
Giulia Di Ruscio,
Andrea Santarelli,
Romina Rocchetti,
Corrado Rubini,
Marco Tomasetti,
Giovanni Giannatempo

Published: August 21, 2013
https://doi.org/10.1371/journal.pone.0071272

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