Pharmacological Reversal of Histone Methylation Presensitizes Pancreatic Cancer Cells to Nucleoside Drugs: In Vitro Optimization and Novel Nanoparticle Delivery Studies

• Sau Wai Hung,

  Affiliation Department of Pharmaceutical and Biomedical Sciences, The University of Georgia, Athens, Georgia, United States of America

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• Hardik Mody ,

  Contributed equally to this work with: Hardik Mody, Sean Marrache

  Affiliation Department of Pharmaceutical and Biomedical Sciences, The University of Georgia, Athens, Georgia, United States of America

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• Sean Marrache ,

  Contributed equally to this work with: Hardik Mody, Sean Marrache

  Affiliation Department of Chemistry, The University of Georgia, Athens, Georgia, United States of America

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• Yangzom D. Bhutia,

  Affiliation Department of Pharmaceutical and Biomedical Sciences, The University of Georgia, Athens, Georgia, United States of America

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• Franklin Davis,

  Affiliation Department of Biological Sciences, The University of Georgia, Athens, Georgia, United States of America

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• Jong Hyun Cho,

  Affiliation Department of Pharmaceutical and Biomedical Sciences, The University of Georgia, Athens, Georgia, United States of America

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• Jason Zastre,

  Affiliation Department of Pharmaceutical and Biomedical Sciences, The University of Georgia, Athens, Georgia, United States of America

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• Shanta Dhar,

  Affiliation Department of Chemistry, The University of Georgia, Athens, Georgia, United States of America

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• Chung K. Chu,

  Affiliation Department of Pharmaceutical and Biomedical Sciences, The University of Georgia, Athens, Georgia, United States of America

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• Rajgopal Govindarajan

  * E-mail: rgovinda@rx.uga.edu

  Affiliation Department of Pharmaceutical and Biomedical Sciences, The University of Georgia, Athens, Georgia, United States of America

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