A Mathematical Model of Cancer Stem Cell Driven Tumor Initiation: Implications of Niche Size and Loss of Homeostatic Regulatory Mechanisms

Open Access

Peer-reviewed

Research Article

Sara N. Gentry,

Affiliation Department of Mathematics, University of Michigan, Ann Arbor, Michigan, United States of America
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Trachette L. Jackson

* E-mail: tjacks@umich.edu

Affiliation Department of Mathematics, University of Michigan, Ann Arbor, Michigan, United States of America
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Stem cells
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Stem cell niche
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Cancer stem cells
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Cell cycle and cell division
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Cell differentiation
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Cancers and neoplasms
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Point mutation
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Tumor stem cells
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