Overexpression of the Toll-Like Receptor (TLR) Signaling Adaptor MYD88, but Lack of Genetic Mutation, in Myelodysplastic Syndromes

Sophie Dimicoli; Yue Wei; Carlos Bueso-Ramos; Hui Yang; Courtney DiNardo; Yu Jia; Hong Zheng; Zhihong Fang; Martin Nguyen; Sherry Pierce; Rui Chen; Hui Wang; Chenghua Wu; Guillermo Garcia-Manero

doi:10.1371/journal.pone.0071120

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Open Access

Peer-reviewed

Research Article

Overexpression of the Toll-Like Receptor (TLR) Signaling Adaptor MYD88, but Lack of Genetic Mutation, in Myelodysplastic Syndromes

Sophie Dimicoli ,

Contributed equally to this work with: Sophie Dimicoli, Yue Wei

Current address: Hématologie clinique et thérapie celllulaire, Hôpital Haut-Lévêque, Pessac, France

Affiliation Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Yue Wei ,

Contributed equally to this work with: Sophie Dimicoli, Yue Wei

* E-mail: ggarciam@mdanderson.org (GGM); ywei@mdanderson.org (YW)

Affiliation Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Carlos Bueso-Ramos,

Affiliation Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Hui Yang,

Affiliation Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Courtney DiNardo,

Affiliation Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Yu Jia,

Affiliation Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Hong Zheng,

Affiliation Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Zhihong Fang,

Affiliation Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Martin Nguyen,

Affiliation Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Sherry Pierce,

Affiliation Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Rui Chen,

Affiliation Department of Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America
⨯
Hui Wang,

Affiliation Department of Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America
⨯
Chenghua Wu,

Affiliation Department of Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America
⨯
Guillermo Garcia-Manero

* E-mail: ggarciam@mdanderson.org (GGM); ywei@mdanderson.org (YW)

Affiliation Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯

Overexpression of the Toll-Like Receptor (TLR) Signaling Adaptor MYD88, but Lack of Genetic Mutation, in Myelodysplastic Syndromes

Sophie Dimicoli,
Yue Wei,
Carlos Bueso-Ramos,
Hui Yang,
Courtney DiNardo,
Yu Jia,
Hong Zheng,
Zhihong Fang,
Martin Nguyen,
Sherry Pierce

Published: August 15, 2013
https://doi.org/10.1371/journal.pone.0071120

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