Impaired Ca2+ Signaling in β-Cells Lacking Leptin Receptors by Cre-loxP Recombination

Open Access

Peer-reviewed

Research Article

Impaired Ca²⁺ Signaling in β-Cells Lacking Leptin Receptors by Cre-loxP Recombination

Eva Tudurí,

Affiliation Department of Cellular and Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada
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Jennifer E. Bruin,

Affiliation Department of Cellular and Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada
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Heather C. Denroche,

Affiliation Department of Cellular and Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada
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Jessica K. Fox,

Affiliation Department of Cellular and Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada
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James D. Johnson,

Affiliations Department of Cellular and Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada, Department of Surgery, University of British Columbia, Vancouver, British Columbia, Canada
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Timothy J. Kieffer

* E-mail: tim.kieffer@ubc.ca

Affiliations Department of Cellular and Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada, Department of Surgery, University of British Columbia, Vancouver, British Columbia, Canada
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Glucose signaling
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Leptin
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Insulin
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Glucose
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Glucose metabolism
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Insulin secretion
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Mouse models
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Genetically modified animals
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