Exposure of Clinical MRSA Heterogeneous Strains to β-Lactams Redirects Metabolism to Optimize Energy Production through the TCA Cycle

Open Access

Peer-reviewed

Research Article

Mignon A. Keaton,

Affiliation Metabolon, Inc., Durham, North Carolina, United States of America
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Roberto R. Rosato,

Affiliation Department of Pathology and Genomic Medicine, Center for Molecular and Translational Human Infectious Diseases Research, The Methodist Hospital Research Institute, Houston, Texas, United States of America
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Konrad B. Plata,

Affiliation Department of Pathology and Genomic Medicine, Center for Molecular and Translational Human Infectious Diseases Research, The Methodist Hospital Research Institute, Houston, Texas, United States of America
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Christopher R. Singh,

Affiliation Department of Pathology and Genomic Medicine, Center for Molecular and Translational Human Infectious Diseases Research, The Methodist Hospital Research Institute, Houston, Texas, United States of America
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Adriana E. Rosato

* E-mail: aerosato@tmhs.org

Affiliation Department of Pathology and Genomic Medicine, Center for Molecular and Translational Human Infectious Diseases Research, The Methodist Hospital Research Institute, Houston, Texas, United States of America
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Citric acid cycle
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Pyruvate
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Gene expression
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Cell walls
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Methicillin-resistant Staphylococcus aureus
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Protein metabolism
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Staphylococcus aureus
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Amino acid metabolism
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