Imbalance between HAT and HDAC Activities in the PBMCs of Patients with Ankylosing Spondylitis or Rheumatoid Arthritis and Influence of HDAC Inhibitors on TNF Alpha Production

• Eric Toussirot ,

  * E-mail : etoussirot@chu-besancon.fr

  Affiliations Clinical Investigation Center Biotherapy CBT-506, University Hospital of Besançon, Besançon, France, Department of Rheumatology, University Hospital of Besançon, Besançon, France, Department of Therapeutics, University of Franche Comté, Besançon, France, UPRES EA 4266, Pathogens and Inflammation Laboratory, SFR FED 4234, University of Franche Comté, Besançon, France

  ⨯
• Wasim Abbas,

  Affiliations UPRES EA 4266, Pathogens and Inflammation Laboratory, SFR FED 4234, University of Franche Comté, Besançon, France, Department of Virology, University Hospital of Besançon, Besançon, France

  ⨯
• Kashif Aziz Khan,

  Affiliations UPRES EA 4266, Pathogens and Inflammation Laboratory, SFR FED 4234, University of Franche Comté, Besançon, France, Department of Virology, University Hospital of Besançon, Besançon, France

  ⨯
• Marion Tissot,

  Affiliation Department of Virology, University Hospital of Besançon, Besançon, France

  ⨯
• Alicia Jeudy,

  Affiliation Department of Virology, University Hospital of Besançon, Besançon, France

  ⨯
• Lucile Baud,

  Affiliation Department of Virology, University Hospital of Besançon, Besançon, France

  ⨯
• Ewa Bertolini,

  Affiliation Department of Rheumatology, University Hospital of Besançon, Besançon, France

  ⨯
• Daniel Wendling,

  Affiliations Department of Rheumatology, University Hospital of Besançon, Besançon, France, UPRES EA 4266, Pathogens and Inflammation Laboratory, SFR FED 4234, University of Franche Comté, Besançon, France

  ⨯
• Georges Herbein

  Affiliations UPRES EA 4266, Pathogens and Inflammation Laboratory, SFR FED 4234, University of Franche Comté, Besançon, France, Department of Virology, University Hospital of Besançon, Besançon, France

  ⨯