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Open Access

Peer-reviewed

Research Article

Preventive Effect of Dipeptidyl Peptidase-4 Inhibitor on Atherosclerosis Is Mainly Attributable to Incretin's Actions in Nondiabetic and Diabetic Apolipoprotein E-Null Mice

Michishige Terasaki,

Affiliation Department of Medicine, Division of Diabetes, Metabolism, and Endocrinology, Showa University School of Medicine, Shinagawa-ku, Tokyo, Japan
⨯
Masaharu Nagashima,

Affiliation Department of Medicine, Division of Diabetes, Metabolism, and Endocrinology, Showa University School of Medicine, Shinagawa-ku, Tokyo, Japan
⨯
Kyoko Nohtomi,

Affiliation Department of Medicine, Division of Diabetes, Metabolism, and Endocrinology, Showa University School of Medicine, Shinagawa-ku, Tokyo, Japan
⨯
Kyoko Kohashi,

Affiliation Department of Medicine, Division of Diabetes, Metabolism, and Endocrinology, Showa University School of Medicine, Shinagawa-ku, Tokyo, Japan
⨯
Masako Tomoyasu,

Affiliation Department of Medicine, Division of Diabetes, Metabolism, and Endocrinology, Showa University School of Medicine, Shinagawa-ku, Tokyo, Japan
⨯
Kyoko Sinmura,

Affiliation Department of Medicine, Division of Diabetes, Metabolism, and Endocrinology, Showa University School of Medicine, Shinagawa-ku, Tokyo, Japan
⨯
Yukinori Nogi,

Affiliation Department of Medicine, Division of Diabetes, Metabolism, and Endocrinology, Showa University School of Medicine, Shinagawa-ku, Tokyo, Japan
⨯
Yuki Katayama,

Affiliation Laboratory of Cardiovascular Medicine, Tokyo University of Pharmacy and Life Sciences, Hachioji-City, Tokyo, Japan
⨯
Kengo Sato,

Affiliation Laboratory of Cardiovascular Medicine, Tokyo University of Pharmacy and Life Sciences, Hachioji-City, Tokyo, Japan
⨯
Fumiko Itoh,

Affiliation Laboratory of Cardiovascular Medicine, Tokyo University of Pharmacy and Life Sciences, Hachioji-City, Tokyo, Japan
⨯
Takuya Watanabe,

Affiliation Laboratory of Cardiovascular Medicine, Tokyo University of Pharmacy and Life Sciences, Hachioji-City, Tokyo, Japan
⨯
Tsutomu Hirano

* E-mail: hirano@med.showa-u.ac.jp

Affiliation Department of Medicine, Division of Diabetes, Metabolism, and Endocrinology, Showa University School of Medicine, Shinagawa-ku, Tokyo, Japan
⨯

Preventive Effect of Dipeptidyl Peptidase-4 Inhibitor on Atherosclerosis Is Mainly Attributable to Incretin's Actions in Nondiabetic and Diabetic Apolipoprotein E-Null Mice

Michishige Terasaki,
Masaharu Nagashima,
Kyoko Nohtomi,
Kyoko Kohashi,
Masako Tomoyasu,
Kyoko Sinmura,
Yukinori Nogi,
Yuki Katayama,
Kengo Sato,
Fumiko Itoh

x

Published: August 13, 2013
https://doi.org/10.1371/journal.pone.0070933

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Diabetes mellitus
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Atherosclerosis
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Mouse models
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Cholesterol
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Gene expression
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Glucose
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