DYRK2 Negatively Regulates Cardiomyocyte Growth by Mediating Repressor Function of GSK-3β on eIF2Bε

Celine S. Weiss; Marco M. Ochs; Marco Hagenmueller; Marcus R. Streit; Pratima Malekar; Johannes H. Riffel; Sebastian J. Buss; Karl H. Weiss; Junichi Sadoshima; Hugo A. Katus; Stefan E. Hardt

doi:10.1371/journal.pone.0070848

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Open Access

Peer-reviewed

Research Article

DYRK2 Negatively Regulates Cardiomyocyte Growth by Mediating Repressor Function of GSK-3β on eIF2Bε

Celine S. Weiss ,

Contributed equally to this work with: Celine S. Weiss, Marco M. Ochs

Affiliation Internal Medicine III, University Hospital Heidelberg and DZHK (German Center for Cardiovascular Research), Heidelberg, Germany
⨯
Marco M. Ochs ,

Contributed equally to this work with: Celine S. Weiss, Marco M. Ochs

Affiliation Internal Medicine III, University Hospital Heidelberg and DZHK (German Center for Cardiovascular Research), Heidelberg, Germany
⨯
Marco Hagenmueller,

Affiliation Internal Medicine III, University Hospital Heidelberg and DZHK (German Center for Cardiovascular Research), Heidelberg, Germany
⨯
Marcus R. Streit,

Affiliation Internal Medicine III, University Hospital Heidelberg and DZHK (German Center for Cardiovascular Research), Heidelberg, Germany
⨯
Pratima Malekar,

Affiliation Internal Medicine III, University Hospital Heidelberg and DZHK (German Center for Cardiovascular Research), Heidelberg, Germany
⨯
Johannes H. Riffel,

Affiliation Internal Medicine III, University Hospital Heidelberg and DZHK (German Center for Cardiovascular Research), Heidelberg, Germany
⨯
Sebastian J. Buss,

Affiliation Internal Medicine III, University Hospital Heidelberg and DZHK (German Center for Cardiovascular Research), Heidelberg, Germany
⨯
Karl H. Weiss,

Affiliation Internal Medicine IV, University Hospital Heidelberg, Heidelberg, Germany
⨯
Junichi Sadoshima,

Affiliation New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America
⨯
Hugo A. Katus,

Affiliation Internal Medicine III, University Hospital Heidelberg and DZHK (German Center for Cardiovascular Research), Heidelberg, Germany
⨯
Stefan E. Hardt

* E-mail: stefan.hardt@med.uni-heidelberg.de

Affiliation Internal Medicine III, University Hospital Heidelberg and DZHK (German Center for Cardiovascular Research), Heidelberg, Germany
⨯

DYRK2 Negatively Regulates Cardiomyocyte Growth by Mediating Repressor Function of GSK-3β on eIF2Bε

Celine S. Weiss,
Marco M. Ochs,
Marco Hagenmueller,
Marcus R. Streit,
Pratima Malekar,
Johannes H. Riffel,
Sebastian J. Buss,
Karl H. Weiss,
Junichi Sadoshima,
Hugo A. Katus

Published: September 4, 2013
https://doi.org/10.1371/journal.pone.0070848

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