Preclinical Evaluation of 4-Methylthiobutyl Isothiocyanate on Liver Cancer and Cancer Stem Cells with Different p53 Status

Evelyn Lamy; Anke Hertrampf; Corinna Herz; Julia Schüler; Miriam Erlacher; Daniela Bertele; Adekunle Bakare; Meike Wagner; Timo Weiland; Ulrich Lauer; Oliver Drognitz; Roman Huber; Sascha Rohn; Torsten Giesemann; Volker Mersch-Sundermann

doi:10.1371/journal.pone.0070846

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Open Access

Peer-reviewed

Research Article

Preclinical Evaluation of 4-Methylthiobutyl Isothiocyanate on Liver Cancer and Cancer Stem Cells with Different p53 Status

Evelyn Lamy ,

* E-mail: evelyn.lamy@uniklinik-freiburg.de

Affiliation Department of Environmental Health Sciences, Freiburg University Medical Center, Freiburg, Germany
⨯
Anke Hertrampf,

Affiliations Department of Environmental Health Sciences, Freiburg University Medical Center, Freiburg, Germany, Faculty of Biology, University of Freiburg, Freiburg, Germany
⨯
Corinna Herz,

Affiliation Department of Environmental Health Sciences, Freiburg University Medical Center, Freiburg, Germany
⨯
Julia Schüler,

Affiliation Department of Experimental Oncology, Oncotest GmbH, Freiburg, Germany
⨯
Miriam Erlacher,

Affiliation Department of Paediatrics and Adolescent Medicine, Freiburg University Medical Center, Freiburg, Germany
⨯
Daniela Bertele,

Affiliation Department of Paediatrics and Adolescent Medicine, Freiburg University Medical Center, Freiburg, Germany
⨯
Adekunle Bakare,

Affiliation Department of Zoology, University of Ibadan, Ibadan, Nigeria
⨯
Meike Wagner,

Affiliation Department of Translational Oncology, Mainz University Medical Center, Mainz, Germany
⨯
Timo Weiland,

Affiliation Department of Internal Medicine I, Medical University Hospital Tübingen, Tübingen, Germany
⨯
Ulrich Lauer,

Affiliation Department of Internal Medicine I, Medical University Hospital Tübingen, Tübingen, Germany
⨯
Oliver Drognitz,

Affiliation Department of Surgery, Freiburg University Medical Center, Freiburg, Germany
⨯
Roman Huber,

Affiliation Department of Environmental Health Sciences, Freiburg University Medical Center, Freiburg, Germany
⨯
Sascha Rohn,

Affiliation Institute for Food Chemistry, University of Hamburg, Hamburg, Germany
⨯
Torsten Giesemann,

Affiliation Department of Experimental Oncology, Oncotest GmbH, Freiburg, Germany
⨯
Volker Mersch-Sundermann

Affiliation Department of Environmental Health Sciences, Freiburg University Medical Center, Freiburg, Germany
⨯

Preclinical Evaluation of 4-Methylthiobutyl Isothiocyanate on Liver Cancer and Cancer Stem Cells with Different p53 Status

Evelyn Lamy,
Anke Hertrampf,
Corinna Herz,
Julia Schüler,
Miriam Erlacher,
Daniela Bertele,
Adekunle Bakare,
Meike Wagner,
Timo Weiland,
Ulrich Lauer

Published: August 2, 2013
https://doi.org/10.1371/journal.pone.0070846

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