The MRC1/CD68 Ratio Is Positively Associated with Adipose Tissue Lipogenesis and with Muscle Mitochondrial Gene Expression in Humans

José María Moreno-Navarrete; Francisco Ortega; María Gómez-Serrano; Eva García-Santos; Wifredo Ricart; Francisco Tinahones; Geltrude Mingrone; Belén Peral; José Manuel Fernández-Real

doi:10.1371/journal.pone.0070810

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Peer-reviewed

Research Article

The MRC1/CD68 Ratio Is Positively Associated with Adipose Tissue Lipogenesis and with Muscle Mitochondrial Gene Expression in Humans

José María Moreno-Navarrete,

Affiliation Service of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain
⨯
Francisco Ortega,

Affiliation Service of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain
⨯
María Gómez-Serrano,

Affiliation Instituto de Investigaciones Biomédicas ‘Alberto Sols’ (IIB), Consejo Superior de Investigaciones Científicas (CSIC) and Universidad Autónoma de Madrid (UAM), Madrid, Spain
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Eva García-Santos,

Affiliation Instituto de Investigaciones Biomédicas ‘Alberto Sols’ (IIB), Consejo Superior de Investigaciones Científicas (CSIC) and Universidad Autónoma de Madrid (UAM), Madrid, Spain
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Wifredo Ricart,

Affiliation Service of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain
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Francisco Tinahones,

Affiliation Department of Endocrinology and Nutrition, Hospital Virgen de la Victoria de Málaga, CIBEROBN Fisiopatologia Obesidad y Nutricion (CB06/03/018), Instituto de Salud Carlos III, Málaga, Spain
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Geltrude Mingrone,

Affiliation Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
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Belén Peral,

Affiliation Instituto de Investigaciones Biomédicas ‘Alberto Sols’ (IIB), Consejo Superior de Investigaciones Científicas (CSIC) and Universidad Autónoma de Madrid (UAM), Madrid, Spain
⨯
José Manuel Fernández-Real

* E-mail: jmfreal@idibgi.org

Affiliation Service of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain
⨯

The MRC1/CD68 Ratio Is Positively Associated with Adipose Tissue Lipogenesis and with Muscle Mitochondrial Gene Expression in Humans

José María Moreno-Navarrete,
Francisco Ortega,
María Gómez-Serrano,
Eva García-Santos,
Wifredo Ricart,
Francisco Tinahones,
Geltrude Mingrone,
Belén Peral,
José Manuel Fernández-Real

Published: August 12, 2013
https://doi.org/10.1371/journal.pone.0070810

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Adipose tissue
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Gene expression
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Obesity
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Macrophages
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Muscle tissue
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Surgical and invasive medical procedures
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Mitochondria
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Digestive system procedures
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