HIV-1 Infected Lymphoid Organs Upregulate Expression and Release of the Cleaved Form of uPAR That Modulates Chemotaxis and Virus Expression

Manuela Nebuloni; Lidia Zawada; Angelita Ferri; Antonella Tosoni; Pietro Zerbi; Massimo Resnati; Guido Poli; Luca Genovese; Massimo Alfano

doi:10.1371/journal.pone.0070606

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Peer-reviewed

Research Article

HIV-1 Infected Lymphoid Organs Upregulate Expression and Release of the Cleaved Form of uPAR That Modulates Chemotaxis and Virus Expression

Manuela Nebuloni,

Affiliation Pathology Unit, “Luigi Sacco” Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy
⨯
Lidia Zawada,

Affiliation Pathology Unit, “Luigi Sacco” Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy
⨯
Angelita Ferri,

Affiliation Pathology Unit, “Luigi Sacco” Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy
⨯
Antonella Tosoni,

Affiliation Pathology Unit, “Luigi Sacco” Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy
⨯
Pietro Zerbi,

Affiliation Pathology Unit, “Luigi Sacco” Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy
⨯
Massimo Resnati,

Affiliation Molecular Genetic Unit, Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy
⨯
Guido Poli,

Affiliations Vita-Salute San Raffaele University, School of Medicine, Milan, Italy, AIDS Immunopathogenesis Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy
⨯
Luca Genovese,

Affiliation AIDS Immunopathogenesis Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy
⨯
Massimo Alfano

* E-mail: massimo.alfano@hsr.it

Affiliation AIDS Immunopathogenesis Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy
⨯

HIV-1 Infected Lymphoid Organs Upregulate Expression and Release of the Cleaved Form of uPAR That Modulates Chemotaxis and Virus Expression

Manuela Nebuloni,
Lidia Zawada,
Angelita Ferri,
Antonella Tosoni,
Pietro Zerbi,
Massimo Resnati,
Guido Poli,
Luca Genovese,
Massimo Alfano

Published: July 29, 2013
https://doi.org/10.1371/journal.pone.0070606

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HIV-1
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Tonsils
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Lymphoid organs
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HIV infections
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HIV
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Chemotaxis
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Viral replication
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Histology
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