Rapid Identification of Antifungal Compounds against Exserohilum rostratum Using High Throughput Drug Repurposing Screens

Wei Sun; Yoon-Dong Park; Janyce A. Sugui; Annette Fothergill; Noel Southall; Paul Shinn; John C. McKew; Kyung J. Kwon-Chung; Wei Zheng; Peter R. Williamson

doi:10.1371/journal.pone.0070506

Loading metrics

Open Access

Peer-reviewed

Research Article

Rapid Identification of Antifungal Compounds against Exserohilum rostratum Using High Throughput Drug Repurposing Screens

Wei Sun ,

Contributed equally to this work with: Wei Sun, Yoon-Dong Park

Affiliation National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Yoon-Dong Park ,

Contributed equally to this work with: Wei Sun, Yoon-Dong Park

Affiliation Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Janyce A. Sugui,

Affiliation Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Annette Fothergill,

Affiliation University of Texas Health Science Center, San Antonio, Texas, United States of America
⨯
Noel Southall,

Affiliation National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Paul Shinn,

Affiliation National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
John C. McKew,

Affiliation National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Kyung J. Kwon-Chung,

Affiliation Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Wei Zheng ,

* E-mail: williamsonpr@mail.nih.gov (PRW); wzheng@mail.nih.gov (WZ)

Affiliation National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Peter R. Williamson

* E-mail: williamsonpr@mail.nih.gov (PRW); wzheng@mail.nih.gov (WZ)

Affiliations Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America, Section of Infectious Diseases, Immunology and International Medicine, University of Illinois College of Medicine, Chicago, Illinois, United States of America
⨯

Rapid Identification of Antifungal Compounds against Exserohilum rostratum Using High Throughput Drug Repurposing Screens

Wei Sun,
Yoon-Dong Park,
Janyce A. Sugui,
Annette Fothergill,
Noel Southall,
Paul Shinn,
John C. McKew,
Kyung J. Kwon-Chung,
Wei Zheng,
Peter R. Williamson

Published: August 21, 2013
https://doi.org/10.1371/journal.pone.0070506

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Antifungals
Is the Subject Area "Antifungals" applicable to this article?

Thanks for your feedback.
Drug screening
Is the Subject Area "Drug screening" applicable to this article?

Thanks for your feedback.
Fungicides
Is the Subject Area "Fungicides" applicable to this article?

Thanks for your feedback.
Amphotericin
Is the Subject Area "Amphotericin" applicable to this article?

Thanks for your feedback.
Drug research and development
Is the Subject Area "Drug research and development" applicable to this article?

Thanks for your feedback.
Drug therapy
Is the Subject Area "Drug therapy" applicable to this article?

Thanks for your feedback.
Cytotoxicity assay
Is the Subject Area "Cytotoxicity assay" applicable to this article?

Thanks for your feedback.
Fungal diseases
Is the Subject Area "Fungal diseases" applicable to this article?

Thanks for your feedback.