Regulators of Global Genome Repair Do Not Respond to DNA Damaging Therapy but Correlate with Survival in Melanoma

Nikola A. Bowden; Katie A. Ashton; Ricardo E. Vilain; Kelly A. Avery-Kiejda; Ryan J. Davey; Heather C. Murray; Timothy Budden; Stephen G. Braye; Xu Dong Zhang; Peter Hersey; Rodney J. Scott

doi:10.1371/journal.pone.0070424

Loading metrics

Open Access

Peer-reviewed

Research Article

Regulators of Global Genome Repair Do Not Respond to DNA Damaging Therapy but Correlate with Survival in Melanoma

Nikola A. Bowden ,

* E-mail: Nikola.Bowden@newcastle.edu.au

Affiliation School of Biomedical Sciences & Pharmacy, Faculty of Health, University of Newcastle, Australia and Hunter Medical Research Institute, Newcastle, NSW, Australia
⨯
Katie A. Ashton,

Affiliation School of Biomedical Sciences & Pharmacy, Faculty of Health, University of Newcastle, Australia and Hunter Medical Research Institute, Newcastle, NSW, Australia
⨯
Ricardo E. Vilain,

Affiliations School of Biomedical Sciences & Pharmacy, Faculty of Health, University of Newcastle, Australia and Hunter Medical Research Institute, Newcastle, NSW, Australia, Hunter Area Pathology Service, John Hunter Hospital, Newcastle, NSW, Australia
⨯
Kelly A. Avery-Kiejda,

Affiliation School of Biomedical Sciences & Pharmacy, Faculty of Health, University of Newcastle, Australia and Hunter Medical Research Institute, Newcastle, NSW, Australia
⨯
Ryan J. Davey,

Affiliation School of Biomedical Sciences & Pharmacy, Faculty of Health, University of Newcastle, Australia and Hunter Medical Research Institute, Newcastle, NSW, Australia
⨯
Heather C. Murray,

Affiliation School of Biomedical Sciences & Pharmacy, Faculty of Health, University of Newcastle, Australia and Hunter Medical Research Institute, Newcastle, NSW, Australia
⨯
Timothy Budden,

Affiliation School of Biomedical Sciences & Pharmacy, Faculty of Health, University of Newcastle, Australia and Hunter Medical Research Institute, Newcastle, NSW, Australia
⨯
Stephen G. Braye,

Affiliation Hunter Area Pathology Service, John Hunter Hospital, Newcastle, NSW, Australia
⨯
Xu Dong Zhang,

Affiliation School of Biomedical Sciences & Pharmacy, Faculty of Health, University of Newcastle, Australia and Hunter Medical Research Institute, Newcastle, NSW, Australia
⨯
Peter Hersey,

Affiliation Kolling Institute, University of Sydney, NSW, Australia
⨯
Rodney J. Scott

Affiliations School of Biomedical Sciences & Pharmacy, Faculty of Health, University of Newcastle, Australia and Hunter Medical Research Institute, Newcastle, NSW, Australia, Hunter Area Pathology Service, John Hunter Hospital, Newcastle, NSW, Australia
⨯

Regulators of Global Genome Repair Do Not Respond to DNA Damaging Therapy but Correlate with Survival in Melanoma

Nikola A. Bowden,
Katie A. Ashton,
Ricardo E. Vilain,
Kelly A. Avery-Kiejda,
Ryan J. Davey,
Heather C. Murray,
Timothy Budden,
Stephen G. Braye,
Xu Dong Zhang,
Peter Hersey

Published: August 5, 2013
https://doi.org/10.1371/journal.pone.0070424

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Melanoma cells
Is the Subject Area "Melanoma cells" applicable to this article?

Thanks for your feedback.
Melanocytes
Is the Subject Area "Melanocytes" applicable to this article?

Thanks for your feedback.
Melanoma
Is the Subject Area "Melanoma" applicable to this article?

Thanks for your feedback.
DNA damage
Is the Subject Area "DNA damage" applicable to this article?

Thanks for your feedback.
Cancer treatment
Is the Subject Area "Cancer treatment" applicable to this article?

Thanks for your feedback.
Genetic causes of cancer
Is the Subject Area "Genetic causes of cancer" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Regulator genes
Is the Subject Area "Regulator genes" applicable to this article?

Thanks for your feedback.