Combination Therapy with Local Radiofrequency Ablation and Systemic Vaccine Enhances Antitumor Immunity and Mediates Local and Distal Tumor Regression

Sofia R. Gameiro; Jack P. Higgins; Matthew R. Dreher; David L. Woods; Goutham Reddy; Bradford J. Wood; Chandan Guha; James W. Hodge

doi:10.1371/journal.pone.0070417

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Peer-reviewed

Research Article

Combination Therapy with Local Radiofrequency Ablation and Systemic Vaccine Enhances Antitumor Immunity and Mediates Local and Distal Tumor Regression

Sofia R. Gameiro,

Affiliation Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Jack P. Higgins,

Affiliation Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Matthew R. Dreher,

Affiliation Center for Interventional Oncology, Radiology, and Imaging Sciences, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
David L. Woods,

Affiliation Center for Interventional Oncology, Radiology, and Imaging Sciences, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Goutham Reddy,

Affiliation Center for Interventional Oncology, Radiology, and Imaging Sciences, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Bradford J. Wood,

Affiliation Center for Interventional Oncology, Radiology, and Imaging Sciences, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Chandan Guha,

Affiliation Department of Radiation Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, New York, New York, United States of America
⨯
James W. Hodge

* E-mail: jh241d@nih.gov

Affiliation Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯

Combination Therapy with Local Radiofrequency Ablation and Systemic Vaccine Enhances Antitumor Immunity and Mediates Local and Distal Tumor Regression

Sofia R. Gameiro,
Jack P. Higgins,
Matthew R. Dreher,
David L. Woods,
Goutham Reddy,
Bradford J. Wood,
Chandan Guha,
James W. Hodge

Published: July 24, 2013
https://doi.org/10.1371/journal.pone.0070417

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