PCR-Induced Transitions Are the Major Source of Error in Cleaned Ultra-Deep Pyrosequencing Data

• Johanna Brodin ,

  * E-mail: johanna.brodin@ki.se

  Affiliation Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden

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• Mattias Mild,

  Affiliations Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden, Department of Virology, Swedish Institute for Infectious Disease Control, Stockholm, Sweden

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• Charlotte Hedskog,

  Affiliation Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden

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• Ellen Sherwood,

  Affiliation Science for Life Laboratory Stockholm, Solna, Sweden

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• Thomas Leitner,

  Affiliation Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

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• Björn Andersson,

  Affiliation Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden

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• Jan Albert

  Affiliation Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden

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