Crystal Structure of the N-Acetyltransferase Domain of Human N-Acetyl-L-Glutamate Synthase in Complex with N-Acetyl-L-Glutamate Provides Insights into Its Catalytic and Regulatory Mechanisms

• Gengxiang Zhao,

  Affiliation Center for Genetic Medicine Research and Department of Integrative Systems Biology, Children’s National Medical Center, The George Washington University, Washington, D. C., United States of America

  ⨯
• Zhongmin Jin,

  Affiliation Southeast Regional Collaborative Access Team, Advanced Photon Source, Argonne National Laboratory, Argonne, Illinois, United States of America

  ⨯
• Norma M. Allewell,

  Affiliation Department of Cell Biology and Molecular Genetics and Department of Chemistry and Biochemistry, College of Computer, Mathematical, and Natural Sciences, University of Maryland, College Park, Maryland, United States of America

  ⨯
• Mendel Tuchman,

  Affiliation Center for Genetic Medicine Research and Department of Integrative Systems Biology, Children’s National Medical Center, The George Washington University, Washington, D. C., United States of America

  ⨯
• Dashuang Shi

  * E-mail: dshi@cnmcresearch.org

  Affiliation Center for Genetic Medicine Research and Department of Integrative Systems Biology, Children’s National Medical Center, The George Washington University, Washington, D. C., United States of America

  ⨯