Ribonucleotide Reductase Large Subunit M1 Predicts Poor Survival Due to Modulation of Proliferative and Invasive Ability of Gastric Cancer

Qinchuan Wang; Xiyong Liu; Jichun Zhou; Yasheng Huang; Shengjie Zhang; Jianguo Shen; Sofia Loera; Xiaoming Yuan; Wenjun Chen; Mei Jin; Stephen Shibata; Yingbin Liu; Peiguo Chu; Linbo Wang; Yun Yen

doi:10.1371/journal.pone.0070191

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Open Access

Peer-reviewed

Research Article

Ribonucleotide Reductase Large Subunit M1 Predicts Poor Survival Due to Modulation of Proliferative and Invasive Ability of Gastric Cancer

Qinchuan Wang ,

Contributed equally to this work with: Qinchuan Wang, Xiyong Liu

Affiliations Department of Surgical Oncology, Affiliated Sir Runrun Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China, Department of Molecular Pharmacology, City of Hope Comprehensive Cancer Center, Duarte, California, United States of America
⨯
Xiyong Liu ,

Contributed equally to this work with: Qinchuan Wang, Xiyong Liu

Affiliation Department of Molecular Pharmacology, City of Hope Comprehensive Cancer Center, Duarte, California, United States of America
⨯
Jichun Zhou,

Affiliation Department of Surgical Oncology, Affiliated Sir Runrun Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China
⨯
Yasheng Huang,

Affiliation Department of Molecular Pharmacology, City of Hope Comprehensive Cancer Center, Duarte, California, United States of America
⨯
Shengjie Zhang,

Affiliation Department of Surgical Oncology, Affiliated Sir Runrun Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China
⨯
Jianguo Shen,

Affiliation Department of Surgical Oncology, Affiliated Sir Runrun Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China
⨯
Sofia Loera,

Affiliation Department of Anatomic Pathology, City of Hope Comprehensive Cancer Center, Duarte, California, United States of America
⨯
Xiaoming Yuan,

Affiliation Department of Surgical Oncology, Affiliated Sir Runrun Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China
⨯
Wenjun Chen,

Affiliation Department of Surgical Oncology, Affiliated Sir Runrun Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China
⨯
Mei Jin,

Affiliation Department of Pathology, Affiliated Sir Runrun Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China
⨯
Stephen Shibata,

Affiliation Department of Medical Oncology, City of Hope Comprehensive Cancer Center, Duarte, California, United States of America
⨯
Yingbin Liu,

Affiliation Department of General Surgery, Shanghai Xinhua Hospital, Shanghai, China
⨯
Peiguo Chu,

Affiliation Department of Anatomic Pathology, City of Hope Comprehensive Cancer Center, Duarte, California, United States of America
⨯
Linbo Wang ,

* E-mail: yyen@coh.org (YY); wanglinbo@medmail.com.cn (LW)

Affiliation Department of Surgical Oncology, Affiliated Sir Runrun Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China
⨯
Yun Yen

* E-mail: yyen@coh.org (YY); wanglinbo@medmail.com.cn (LW)

Affiliations Department of Surgical Oncology, Affiliated Sir Runrun Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China, Department of Molecular Pharmacology, City of Hope Comprehensive Cancer Center, Duarte, California, United States of America, Taipei Medical University, Taipei, Taiwan
⨯

Ribonucleotide Reductase Large Subunit M1 Predicts Poor Survival Due to Modulation of Proliferative and Invasive Ability of Gastric Cancer

Qinchuan Wang,
Xiyong Liu,
Jichun Zhou,
Yasheng Huang,
Shengjie Zhang,
Jianguo Shen,
Sofia Loera,
Xiaoming Yuan,
Wenjun Chen,
Mei Jin

Published: July 29, 2013
https://doi.org/10.1371/journal.pone.0070191

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