Interleukin-5 Supports the Expansion of Fas Ligand-Expressing Killer B Cells that Induce Antigen-Specific Apoptosis of CD4+ T Cells and Secrete Interleukin-10

Open Access

Peer-reviewed

Research Article

Interleukin-5 Supports the Expansion of Fas Ligand-Expressing Killer B Cells that Induce Antigen-Specific Apoptosis of CD4⁺ T Cells and Secrete Interleukin-10

Matthew W. Klinker,

Affiliations Graduate Program in Immunology, University of Michigan, Ann Arbor, Michigan, United States of America, Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America
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Tamra J. Reed,

Affiliation Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America
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David A. Fox,

Affiliations Graduate Program in Immunology, University of Michigan, Ann Arbor, Michigan, United States of America, Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America
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Steven K. Lundy

* E-mail: sklundy@med.umich.edu

Affiliations Graduate Program in Immunology, University of Michigan, Ann Arbor, Michigan, United States of America, Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America
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B cells
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T cells
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Apoptosis
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Cell staining
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Mouse models
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Fibroblasts
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Secretion
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Cytokines
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