Visualisation of γH2AX Foci Caused by Heavy Ion Particle Traversal; Distinction between Core Track versus Non-Track Damage

Nakako Izumi Nakajima; Holly Brunton; Ritsuko Watanabe; Amruta Shrikhande; Ryoichi Hirayama; Naruhiro Matsufuji; Akira Fujimori; Takeshi Murakami; Ryuichi Okayasu; Penny Jeggo; Atsushi Shibata

doi:10.1371/journal.pone.0070107

Loading metrics

Open Access

Peer-reviewed

Research Article

Visualisation of γH2AX Foci Caused by Heavy Ion Particle Traversal; Distinction between Core Track versus Non-Track Damage

Nakako Izumi Nakajima,

Affiliation Research Center for Charged Particle Therapy and International Open Laboratory, National Institute of Radiological Sciences, Chiba, Japan
⨯
Holly Brunton,

Affiliation Genome Damage and Stability Centre, University of Sussex, Brighton, East Sussex, United Kingdom
⨯
Ritsuko Watanabe,

Affiliation Japan Atomic Energy Agency, Tokai, Japan
⨯
Amruta Shrikhande,

Affiliation Genome Damage and Stability Centre, University of Sussex, Brighton, East Sussex, United Kingdom
⨯
Ryoichi Hirayama,

Affiliation Research Center for Charged Particle Therapy and International Open Laboratory, National Institute of Radiological Sciences, Chiba, Japan
⨯
Naruhiro Matsufuji,

Affiliation Research Center for Charged Particle Therapy and International Open Laboratory, National Institute of Radiological Sciences, Chiba, Japan
⨯
Akira Fujimori,

Affiliation Research Center for Charged Particle Therapy and International Open Laboratory, National Institute of Radiological Sciences, Chiba, Japan
⨯
Takeshi Murakami,

Affiliation Research Center for Charged Particle Therapy and International Open Laboratory, National Institute of Radiological Sciences, Chiba, Japan
⨯
Ryuichi Okayasu,

Affiliation Research Center for Charged Particle Therapy and International Open Laboratory, National Institute of Radiological Sciences, Chiba, Japan
⨯
Penny Jeggo ,

* E-mail: p.a.jeggo@sussex.ac.uk (PJ); as303@sussex.ac.uk (AS)

Affiliation Genome Damage and Stability Centre, University of Sussex, Brighton, East Sussex, United Kingdom
⨯
Atsushi Shibata

* E-mail: p.a.jeggo@sussex.ac.uk (PJ); as303@sussex.ac.uk (AS)

Current address: Advanced Scientific Research Leaders Development Unit, Gunma University, Maebashi, Japan

Affiliation Genome Damage and Stability Centre, University of Sussex, Brighton, East Sussex, United Kingdom
⨯

Visualisation of γH2AX Foci Caused by Heavy Ion Particle Traversal; Distinction between Core Track versus Non-Track Damage

Nakako Izumi Nakajima,
Holly Brunton,
Ritsuko Watanabe,
Amruta Shrikhande,
Ryoichi Hirayama,
Naruhiro Matsufuji,
Akira Fujimori,
Takeshi Murakami,
Ryuichi Okayasu,
Penny Jeggo

Published: August 14, 2013
https://doi.org/10.1371/journal.pone.0070107

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

DNA repair
Is the Subject Area "DNA repair" applicable to this article?

Thanks for your feedback.
DNA damage
Is the Subject Area "DNA damage" applicable to this article?

Thanks for your feedback.
X-ray radiography
Is the Subject Area "X-ray radiography" applicable to this article?

Thanks for your feedback.
Mitosis
Is the Subject Area "Mitosis" applicable to this article?

Thanks for your feedback.
Non-homologous end joining
Is the Subject Area "Non-homologous end joining" applicable to this article?

Thanks for your feedback.
Radiation therapy
Is the Subject Area "Radiation therapy" applicable to this article?

Thanks for your feedback.
Gamma rays
Is the Subject Area "Gamma rays" applicable to this article?

Thanks for your feedback.
Phosphorylation
Is the Subject Area "Phosphorylation" applicable to this article?

Thanks for your feedback.