Regulation of the Tumor Suppressor PTEN through Exosomes: A Diagnostic Potential for Prostate Cancer

Kathleen Gabriel; Alistair Ingram; Richard Austin; Anil Kapoor; Damu Tang; Fadwa Majeed; Talha Qureshi; Khalid Al-Nedawi

doi:10.1371/journal.pone.0070047

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Open Access

Peer-reviewed

Research Article

Regulation of the Tumor Suppressor PTEN through Exosomes: A Diagnostic Potential for Prostate Cancer

Kathleen Gabriel,

Affiliations Division of Nephrology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada, Hamilton Centre for Kidney Research (HCKR), St. Joseph’s Hospital, Hamilton, Ontario, Canada
⨯
Alistair Ingram,

Affiliations Division of Nephrology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada, Hamilton Centre for Kidney Research (HCKR), St. Joseph’s Hospital, Hamilton, Ontario, Canada
⨯
Richard Austin,

Affiliations Division of Nephrology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada, Hamilton Centre for Kidney Research (HCKR), St. Joseph’s Hospital, Hamilton, Ontario, Canada
⨯
Anil Kapoor,

Affiliation Division of Urology, Department of Surgery, McMaster University, Hamilton, Ontario, Canada
⨯
Damu Tang,

Affiliations Division of Nephrology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada, Hamilton Centre for Kidney Research (HCKR), St. Joseph’s Hospital, Hamilton, Ontario, Canada
⨯
Fadwa Majeed,

Affiliations Division of Nephrology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada, Hamilton Centre for Kidney Research (HCKR), St. Joseph’s Hospital, Hamilton, Ontario, Canada
⨯
Talha Qureshi,

Affiliations Division of Nephrology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada, Hamilton Centre for Kidney Research (HCKR), St. Joseph’s Hospital, Hamilton, Ontario, Canada
⨯
Khalid Al-Nedawi

* E-mail: alnedaw@mcmaster.ca

Affiliations Division of Nephrology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada, Hamilton Centre for Kidney Research (HCKR), St. Joseph’s Hospital, Hamilton, Ontario, Canada
⨯

Regulation of the Tumor Suppressor PTEN through Exosomes: A Diagnostic Potential for Prostate Cancer

Kathleen Gabriel,
Alistair Ingram,
Richard Austin,
Anil Kapoor,
Damu Tang,
Fadwa Majeed,
Talha Qureshi,
Khalid Al-Nedawi

Published: July 25, 2013
https://doi.org/10.1371/journal.pone.0070047

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DU145 cells
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Small interfering RNA
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