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Open Access

Peer-reviewed

Research Article

Folliculin Contributes to VHL Tumor Suppressing Activity in Renal Cancer through Regulation of Autophagy

Prabhat Bastola ,

Contributed equally to this work with: Prabhat Bastola, Yiwen Stratton

Affiliation Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America
⨯
Yiwen Stratton ,

Contributed equally to this work with: Prabhat Bastola, Yiwen Stratton

Affiliation Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America
⨯
Emily Kellner,

Affiliation Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America
⨯
Olga Mikhaylova,

Affiliation Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America
⨯
Ying Yi,

Affiliation Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America
⨯
Maureen A. Sartor,

Affiliation Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America
⨯
Mario Medvedovic,

Affiliation Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America
⨯
Jacek Biesiada,

Affiliation Division of Biomedical Informatics, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America
⨯
Jarek Meller,

Affiliations Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America, Division of Biomedical Informatics, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America, Department of Informatics, Nicolas Copernicus University, Torun, Poland
⨯
Maria F. Czyzyk-Krzeska

* E-mail: Maria.Czyzykkrzeska@uc.edu

Affiliations Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America, VA Research Service, Department of Veterans Affairs, Cincinnati, Ohio, United States of America
⨯

Folliculin Contributes to VHL Tumor Suppressing Activity in Renal Cancer through Regulation of Autophagy

Prabhat Bastola,
Yiwen Stratton,
Emily Kellner,
Olga Mikhaylova,
Ying Yi,
Maureen A. Sartor,
Mario Medvedovic,
Jacek Biesiada,
Jarek Meller,
Maria F. Czyzyk-Krzeska

x

Published: July 29, 2013
https://doi.org/10.1371/journal.pone.0070030

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Renal cancer
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Kidneys
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Autophagic cell death
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Gene expression
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Renal cell carcinoma
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Tumor suppressor genes
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Cancers and neoplasms
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Genetic loci
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