Metformin, a Diabetes Drug, Eliminates Tumor-Initiating Hepatocellular Carcinoma Cells

• Tomoko Saito ,

  Contributed equally to this work with: Tomoko Saito, Tetsuhiro Chiba

  Affiliations Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan, Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

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• Tetsuhiro Chiba ,

  Contributed equally to this work with: Tomoko Saito, Tetsuhiro Chiba

  * E-mail: techiba@faculty.chiba-u.jp

  Affiliations Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan, Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

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• Kaori Yuki,

  Affiliations Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan, Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

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• Yoh Zen,

  Affiliation Institute of Liver Studies, King’s College Hospital, London, United Kingdom

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• Motohiko Oshima,

  Affiliation Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

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• Shuhei Koide,

  Affiliation Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

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• Tenyu Motoyama,

  Affiliation Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan

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• Sadahisa Ogasawara,

  Affiliation Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan

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• Eiichiro Suzuki,

  Affiliation Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan

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• Yoshihiko Ooka,

  Affiliation Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan

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• Akinobu Tawada,

  Affiliation Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan

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• Motohisa Tada,

  Affiliation Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan

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• Fumihiko Kanai,

  Affiliation Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan

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• Yuichi Takiguchi,

  Affiliation Department of Medical Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan

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• Atsushi Iwama,

  Affiliation Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

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•  [ ... ],
• Osamu Yokosuka

  Affiliation Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan

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