Expression of the ARPC4 Subunit of Human Arp2/3 Severely Affects Mycobacterium tuberculosis Growth and Suppresses Immunogenic Response in Murine Macrophages

Anamika Ghosh; Sultan Tousif; Debapriya Bhattacharya; Sachin K. Samuchiwal; Kuhulika Bhalla; Megha Tharad; Sushil Kumar; Prem Prakash; Purnima Kumar; Gobardhan Das; Anand Ranganathan

doi:10.1371/journal.pone.0069949

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Open Access

Peer-reviewed

Research Article

Expression of the ARPC4 Subunit of Human Arp2/3 Severely Affects Mycobacterium tuberculosis Growth and Suppresses Immunogenic Response in Murine Macrophages

Anamika Ghosh,

Affiliation Recombinant Gene Products Group, International Centre for Genetic Engineering and Biotechnology, ICGEB Campus, Aruna Asaf Ali Marg, New Delhi, India
⨯
Sultan Tousif ,

Contributed equally to this work with: Sultan Tousif, Debapriya Bhattacharya

Affiliations Immunology Group, International Centre for Genetic Engineering and Biotechnology, ICGEB Campus, Aruna Asaf Ali Marg, New Delhi, India, Department of Biochemistry, University of Calcutta, Kolkata, India
⨯
Debapriya Bhattacharya ,

Contributed equally to this work with: Sultan Tousif, Debapriya Bhattacharya

Affiliation Immunology Group, International Centre for Genetic Engineering and Biotechnology, ICGEB Campus, Aruna Asaf Ali Marg, New Delhi, India
⨯
Sachin K. Samuchiwal,

Affiliation Recombinant Gene Products Group, International Centre for Genetic Engineering and Biotechnology, ICGEB Campus, Aruna Asaf Ali Marg, New Delhi, India
⨯
Kuhulika Bhalla,

Affiliation Recombinant Gene Products Group, International Centre for Genetic Engineering and Biotechnology, ICGEB Campus, Aruna Asaf Ali Marg, New Delhi, India
⨯
Megha Tharad,

Affiliation Recombinant Gene Products Group, International Centre for Genetic Engineering and Biotechnology, ICGEB Campus, Aruna Asaf Ali Marg, New Delhi, India
⨯
Sushil Kumar,

Affiliation Recombinant Gene Products Group, International Centre for Genetic Engineering and Biotechnology, ICGEB Campus, Aruna Asaf Ali Marg, New Delhi, India
⨯
Prem Prakash,

Affiliation Recombinant Gene Products Group, International Centre for Genetic Engineering and Biotechnology, ICGEB Campus, Aruna Asaf Ali Marg, New Delhi, India
⨯
Purnima Kumar,

Affiliation Recombinant Gene Products Group, International Centre for Genetic Engineering and Biotechnology, ICGEB Campus, Aruna Asaf Ali Marg, New Delhi, India
⨯
Gobardhan Das ,

* E-mail: dasgo@icgeb.res.in (GD); anand@icgeb.res.in (AR)

Affiliations Immunology Group, International Centre for Genetic Engineering and Biotechnology, ICGEB Campus, Aruna Asaf Ali Marg, New Delhi, India, Kwazulu-Natal Research Institute for tuberculosis and HIV, University of Kwazulu-Natal, Durban, South Africa
⨯
Anand Ranganathan

* E-mail: dasgo@icgeb.res.in (GD); anand@icgeb.res.in (AR)

Affiliation Recombinant Gene Products Group, International Centre for Genetic Engineering and Biotechnology, ICGEB Campus, Aruna Asaf Ali Marg, New Delhi, India
⨯

Expression of the ARPC4 Subunit of Human Arp2/3 Severely Affects Mycobacterium tuberculosis Growth and Suppresses Immunogenic Response in Murine Macrophages

Anamika Ghosh,
Sultan Tousif,
Debapriya Bhattacharya,
Sachin K. Samuchiwal,
Kuhulika Bhalla,
Megha Tharad,
Sushil Kumar,
Prem Prakash,
Purnima Kumar,
Gobardhan Das

Published: July 22, 2013
https://doi.org/10.1371/journal.pone.0069949

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