Tocilizumab Induced Acquired Factor XIII Deficiency in Patients with Rheumatoid Arthritis

Sho Mokuda; Yosuke Murata; Naoya Sawada; Kenichiro Matoba; Akihiro Yamada; Makoto Onishi; Yasuaki Okuda; Kazuo Jouyama; Eiji Sugiyama; Kiyoshi Takasugi

doi:10.1371/journal.pone.0069944

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Open Access

Peer-reviewed

Research Article

Tocilizumab Induced Acquired Factor XIII Deficiency in Patients with Rheumatoid Arthritis

Sho Mokuda ,

* E-mail: bachblau_since2001@yahoo.co.jp

Affiliations Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima City, Hiroshima, Japan, Department of Internal Medicine, Center for Rheumatic Diseases, Dohgo Spa Hospital, Matsuyama City, Ehime, Japan
⨯
Yosuke Murata,

Affiliation Department of Internal Medicine, Center for Rheumatic Diseases, Dohgo Spa Hospital, Matsuyama City, Ehime, Japan
⨯
Naoya Sawada,

Affiliation Department of Internal Medicine, Center for Rheumatic Diseases, Dohgo Spa Hospital, Matsuyama City, Ehime, Japan
⨯
Kenichiro Matoba,

Affiliation Department of Internal Medicine, Center for Rheumatic Diseases, Dohgo Spa Hospital, Matsuyama City, Ehime, Japan
⨯
Akihiro Yamada,

Affiliation Department of Internal Medicine, Center for Rheumatic Diseases, Dohgo Spa Hospital, Matsuyama City, Ehime, Japan
⨯
Makoto Onishi,

Affiliation Department of Internal Medicine, Center for Rheumatic Diseases, Dohgo Spa Hospital, Matsuyama City, Ehime, Japan
⨯
Yasuaki Okuda,

Affiliation Department of Internal Medicine, Center for Rheumatic Diseases, Dohgo Spa Hospital, Matsuyama City, Ehime, Japan
⨯
Kazuo Jouyama,

Affiliation Department of Internal Medicine, Center for Rheumatic Diseases, Dohgo Spa Hospital, Matsuyama City, Ehime, Japan
⨯
Eiji Sugiyama,

Affiliation Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima City, Hiroshima, Japan
⨯
Kiyoshi Takasugi

Affiliation Department of Internal Medicine, Center for Rheumatic Diseases, Dohgo Spa Hospital, Matsuyama City, Ehime, Japan
⨯

Tocilizumab Induced Acquired Factor XIII Deficiency in Patients with Rheumatoid Arthritis

Sho Mokuda,
Yosuke Murata,
Naoya Sawada,
Kenichiro Matoba,
Akihiro Yamada,
Makoto Onishi,
Yasuaki Okuda,
Kazuo Jouyama,
Eiji Sugiyama,
Kiyoshi Takasugi

Published: August 1, 2013
https://doi.org/10.1371/journal.pone.0069944

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