A Re-Analysis of the Cochrane Library Data: The Dangers of Unobserved Heterogeneity in Meta-Analyses

Open Access

Peer-reviewed

Research Article

Evangelos Kontopantelis ,

* E-mail: e.kontopantelis@manchester.ac.uk

Affiliations Centre for Primary Care, NIHR School for Primary Care Research, Institute of Population Health, University of Manchester, Manchester, United Kingdom, Centre for Biostatistics, Institute of Population Health, University of Manchester, Manchester, United Kingdom, Centre for Health Informatics, Institute of Population Health, University of Manchester, Manchester, United Kingdom
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David A. Springate,

Affiliations Centre for Primary Care, NIHR School for Primary Care Research, Institute of Population Health, University of Manchester, Manchester, United Kingdom, Centre for Biostatistics, Institute of Population Health, University of Manchester, Manchester, United Kingdom
⨯
David Reeves

Affiliations Centre for Primary Care, NIHR School for Primary Care Research, Institute of Population Health, University of Manchester, Manchester, United Kingdom, Centre for Biostatistics, Institute of Population Health, University of Manchester, Manchester, United Kingdom
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Metaanalysis
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Simulation and modeling
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Systematic reviews
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Computer software
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Skewness
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Adverse events
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Antipsychotics
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Randomized controlled trials
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