Prostate Cancer Stem Cell-Targeted Efficacy of a New-Generation Taxoid, SBT-1214 and Novel Polyenolic Zinc-Binding Curcuminoid, CMC2.24

Galina I. Botchkina; Edison S. Zuniga; Rebecca H. Rowehl; Rosa Park; Rahuldev Bhalla; Agnieszka B. Bialkowska; Francis Johnson; Lorne M. Golub; Yu Zhang; Iwao Ojima; Kenneth R. Shroyer

doi:10.1371/journal.pone.0069884

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Peer-reviewed

Research Article

Prostate Cancer Stem Cell-Targeted Efficacy of a New-Generation Taxoid, SBT-1214 and Novel Polyenolic Zinc-Binding Curcuminoid, CMC2.24

Galina I. Botchkina ,

* E-mail: gbotchkina@stonybrookmedicine.edu

Affiliations Department of Pathology, Stony Brook University Medical Center, Stony Brook, New York, United States of America, Institute of Chemical Biology & Drug Development, Stony Brook University, Stony Brook, New York, United States of America
⨯
Edison S. Zuniga,

Affiliations Institute of Chemical Biology & Drug Development, Stony Brook University, Stony Brook, New York, United States of America, Department of Chemistry, Stony Brook University, Stony Brook, New York, United States of America
⨯
Rebecca H. Rowehl,

Affiliation Department of Pathology, Stony Brook University Medical Center, Stony Brook, New York, United States of America
⨯
Rosa Park,

Affiliation Department of Urology, Stony Brook University Medical Center, Stony Brook, New York, United States of America
⨯
Rahuldev Bhalla,

Affiliation Department of Urology, Stony Brook University Medical Center, Stony Brook, New York, United States of America
⨯
Agnieszka B. Bialkowska,

Affiliation Department of Medicine, Stony Brook University Medical Center, Stony Brook, New York, United States of America
⨯
Francis Johnson,

Affiliations Department of Chemistry, Stony Brook University, Stony Brook, New York, United States of America, Department of Pharmacological Sciences, Stony Brook University, Stony Brook, New York, United States of America, Chem-Master Int. Inc., Stony Brook University, Stony Brook, New York, United States of America
⨯
Lorne M. Golub,

Affiliation Department of Oral Biology & Pathology, Stony Brook University, Stony Brook, New York, United States of America
⨯
Yu Zhang,

Affiliation Department of Chemistry, Stony Brook University, Stony Brook, New York, United States of America
⨯
Iwao Ojima,

Affiliations Institute of Chemical Biology & Drug Development, Stony Brook University, Stony Brook, New York, United States of America, Department of Chemistry, Stony Brook University, Stony Brook, New York, United States of America
⨯
Kenneth R. Shroyer

Affiliation Department of Pathology, Stony Brook University Medical Center, Stony Brook, New York, United States of America
⨯

Prostate Cancer Stem Cell-Targeted Efficacy of a New-Generation Taxoid, SBT-1214 and Novel Polyenolic Zinc-Binding Curcuminoid, CMC2.24

Galina I. Botchkina,
Edison S. Zuniga,
Rebecca H. Rowehl,
Rosa Park,
Rahuldev Bhalla,
Agnieszka B. Bialkowska,
Francis Johnson,
Lorne M. Golub,
Yu Zhang,
Iwao Ojima

Published: September 24, 2013
https://doi.org/10.1371/journal.pone.0069884

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