An Activating Mutation Reveals a Second Binding Mode of the Integrin α2 I Domain to the GFOGER Motif in Collagens

Open Access

Peer-reviewed

Research Article

Federico Carafoli ,

Contributed equally to this work with: Federico Carafoli, Samir W. Hamaia

Affiliation Department of Life Sciences, Imperial College London, London, United Kingdom
⨯
Samir W. Hamaia ,

Contributed equally to this work with: Federico Carafoli, Samir W. Hamaia

Affiliation Department of Biochemistry, University of Cambridge, Downing Site, Cambridge, United Kingdom
⨯
Dominique Bihan,

Affiliation Department of Biochemistry, University of Cambridge, Downing Site, Cambridge, United Kingdom
⨯
Erhard Hohenester,

Affiliation Department of Life Sciences, Imperial College London, London, United Kingdom
⨯
Richard W. Farndale

* E-mail: rwf10@cam.ac.uk

Affiliation Department of Biochemistry, University of Cambridge, Downing Site, Cambridge, United Kingdom
⨯

Reader Comments (0)

Collagens
Is the Subject Area "Collagens" applicable to this article?

Thanks for your feedback.
Integrins
Is the Subject Area "Integrins" applicable to this article?

Thanks for your feedback.
Crystal structure
Is the Subject Area "Crystal structure" applicable to this article?

Thanks for your feedback.
Crystallization
Is the Subject Area "Crystallization" applicable to this article?

Thanks for your feedback.
Arginine
Is the Subject Area "Arginine" applicable to this article?

Thanks for your feedback.
Electron density
Is the Subject Area "Electron density" applicable to this article?

Thanks for your feedback.
Glutamic acid
Is the Subject Area "Glutamic acid" applicable to this article?

Thanks for your feedback.
Phenylalanine
Is the Subject Area "Phenylalanine" applicable to this article?

Thanks for your feedback.