C5a Regulates IL-12+DC Migration to Induce Pathogenic Th1 and Th17 Cells in Sepsis

Ning Ma; Chen Xing; He Xiao; Yi Wang; Ke Wang; Chunmei Hou; Gencheng Han; Guojiang Chen; Bernadette Marrero; Yujuan Wang; Beifen Shen; Yan Li; Renxi Wang

doi:10.1371/journal.pone.0069779

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Open Access

Peer-reviewed

Research Article

C5a Regulates IL-12⁺DC Migration to Induce Pathogenic Th1 and Th17 Cells in Sepsis

Ning Ma ,

Contributed equally to this work with: Ning Ma, Chen Xing, He Xiao

Affiliations Laboratory of Immunology, Institute of Basic Medical Sciences, Beijing, China, Department of Rheumatology, First hospital of Jilin University, Changchun, China
⨯
Chen Xing ,

Contributed equally to this work with: Ning Ma, Chen Xing, He Xiao

Affiliation Laboratory of Immunology, Institute of Basic Medical Sciences, Beijing, China
⨯
He Xiao ,

Contributed equally to this work with: Ning Ma, Chen Xing, He Xiao

Affiliation Laboratory of Immunology, Institute of Basic Medical Sciences, Beijing, China
⨯
Yi Wang,

Affiliation Laboratory of Immunology, Institute of Basic Medical Sciences, Beijing, China
⨯
Ke Wang,

Affiliation Laboratory of Immunology, Institute of Basic Medical Sciences, Beijing, China
⨯
Chunmei Hou,

Affiliation Laboratory of Immunology, Institute of Basic Medical Sciences, Beijing, China
⨯
Gencheng Han,

Affiliation Laboratory of Immunology, Institute of Basic Medical Sciences, Beijing, China
⨯
Guojiang Chen,

Affiliation Laboratory of Immunology, Institute of Basic Medical Sciences, Beijing, China
⨯
Bernadette Marrero,

Affiliation Molecular Immunology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Yujuan Wang,

Affiliation Immunopathology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Beifen Shen,

Affiliation Laboratory of Immunology, Institute of Basic Medical Sciences, Beijing, China
⨯
Yan Li ,

* E-mail: wang_renxi@yahoo.com (RW); liyan62033@yahoo.com.cn (YL)

Affiliation Laboratory of Immunology, Institute of Basic Medical Sciences, Beijing, China
⨯
Renxi Wang

* E-mail: wang_renxi@yahoo.com (RW); liyan62033@yahoo.com.cn (YL)

Affiliation Laboratory of Immunology, Institute of Basic Medical Sciences, Beijing, China
⨯

C5a Regulates IL-12⁺DC Migration to Induce Pathogenic Th1 and Th17 Cells in Sepsis

Ning Ma,
Chen Xing,
He Xiao,
Yi Wang,
Ke Wang,
Chunmei Hou,
Gencheng Han,
Guojiang Chen,
Bernadette Marrero,
Yujuan Wang

Published: July 23, 2013
https://doi.org/10.1371/journal.pone.0069779

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Cell staining
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Enzyme-linked immunoassays
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