Synthesis, Structure and Antibacterial Activity of Potent DNA Gyrase Inhibitors: N′-Benzoyl-3-(4-Bromophenyl)-1H-Pyrazole-5-Carbohydrazide Derivatives

Open Access

Peer-reviewed

Research Article

Juan Sun ,

Contributed equally to this work with: Juan Sun, Peng-Cheng Lv

Affiliation State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China
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Peng-Cheng Lv ,

Contributed equally to this work with: Juan Sun, Peng-Cheng Lv

Affiliation State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China
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Yong Yin,

Affiliation State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China
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Rong-Ju Yuan,

Affiliation School of Life Sciences, Shandong University of Technology, Zibo, China
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Jian Ma,

Affiliation School of Life Sciences, Shandong University of Technology, Zibo, China
⨯
Hai-Liang Zhu

* E-mail: zhuhl@nju.edu.cn

Affiliations State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, China, School of Life Sciences, Shandong University of Technology, Zibo, China
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Antibacterials
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Staphylococcus aureus
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Bacillus subtilis
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Crystal structure
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Chemical synthesis
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Molecular docking
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Benzene
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DNA structure
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