Cytosolic PhospholipaseA2 Inhibition with PLA-695 Radiosensitizes Tumors in Lung Cancer Animal Models

Dinesh Thotala; Jeffrey M. Craft; Daniel J. Ferraro; Rama P. Kotipatruni; Sandeep R. Bhave; Jerry J. Jaboin; Dennis E. Hallahan

doi:10.1371/journal.pone.0069688

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Peer-reviewed

Research Article

Cytosolic PhospholipaseA2 Inhibition with PLA-695 Radiosensitizes Tumors in Lung Cancer Animal Models

Dinesh Thotala ,

Contributed equally to this work with: Dinesh Thotala, Jeffrey M. Craft

Affiliations Department of Radiation Oncology, Washington University in St. Louis, St. Louis, Missouri, United States of America, Siteman Cancer Center, Washington University in St. Louis, St. Louis, Missouri, United States of America
⨯
Jeffrey M. Craft ,

Contributed equally to this work with: Dinesh Thotala, Jeffrey M. Craft

Affiliation Department of Radiation Oncology, Washington University in St. Louis, St. Louis, Missouri, United States of America
⨯
Daniel J. Ferraro,

Affiliation Department of Radiation Oncology, Washington University in St. Louis, St. Louis, Missouri, United States of America
⨯
Rama P. Kotipatruni,

Affiliation Department of Radiation Oncology, Washington University in St. Louis, St. Louis, Missouri, United States of America
⨯
Sandeep R. Bhave,

Affiliation School of Medicine, Washington University in St. Louis, St. Louis, Missouri, United States of America
⨯
Jerry J. Jaboin,

Affiliations Department of Radiation Oncology, Washington University in St. Louis, St. Louis, Missouri, United States of America, Siteman Cancer Center, Washington University in St. Louis, St. Louis, Missouri, United States of America
⨯
Dennis E. Hallahan

* E-mail: dhallahan@radonc.wustl.edu

Affiliations Department of Radiation Oncology, Washington University in St. Louis, St. Louis, Missouri, United States of America, Siteman Cancer Center, Washington University in St. Louis, St. Louis, Missouri, United States of America, Hope Center, Washington University in St. Louis, St. Louis, Missouri, United States of America, Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri, United States of America
⨯

Cytosolic PhospholipaseA2 Inhibition with PLA-695 Radiosensitizes Tumors in Lung Cancer Animal Models

Dinesh Thotala,
Jeffrey M. Craft,
Daniel J. Ferraro,
Rama P. Kotipatruni,
Sandeep R. Bhave,
Jerry J. Jaboin,
Dennis E. Hallahan

Published: July 19, 2013
https://doi.org/10.1371/journal.pone.0069688

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