ERK Positive Feedback Regulates a Widespread Network of Tyrosine Phosphorylation Sites across Canonical T Cell Signaling and Actin Cytoskeletal Proteins in Jurkat T Cells

Open Access

Peer-reviewed

Research Article

Ynes A. Helou,

Affiliation Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, Rhode Island, United States of America
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Vinh Nguyen,

Affiliation Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, United States of America
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Samantha P. Beik,

Affiliation Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, United States of America
⨯
Arthur R. Salomon

* E-mail: art@drsalomon.com

Affiliations Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, Rhode Island, United States of America, Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, United States of America, Department of Chemistry, Brown University, Providence, Rhode Island, United States of America
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Phosphorylation
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T cells
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TCR signaling cascade
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ERK signaling cascade
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Stable isotope labeling by amino acids in cell culture
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T cell receptors
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Tyrosine
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Protein kinase signaling cascade
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