Emerging Role of Calcium-Activated Potassium Channel in the Regulation of Cell Viability Following Potassium Ions Challenge in HEK293 Cells and Pharmacological Modulation

Domenico Tricarico; Antonietta Mele; Sara Calzolaro; Gianluigi Cannone; Giulia Maria Camerino; Maria Maddalena Dinardo; Ramon Latorre; Diana Conte Camerino

doi:10.1371/journal.pone.0069551

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Peer-reviewed

Research Article

Emerging Role of Calcium-Activated Potassium Channel in the Regulation of Cell Viability Following Potassium Ions Challenge in HEK293 Cells and Pharmacological Modulation

Domenico Tricarico ,

* E-mail: domenico.tricarico@uniba.it

Affiliations Department of Pharmacy-Drug-Science, University of Bari, Bari, Italy, Centro de Neurociencias de Valparaíso, Facultad de Ciencias, Universidad de Valparaiso, Valparaíso, Chile
⨯
Antonietta Mele,

Affiliations Department of Pharmacy-Drug-Science, University of Bari, Bari, Italy, Centro de Neurociencias de Valparaíso, Facultad de Ciencias, Universidad de Valparaiso, Valparaíso, Chile
⨯
Sara Calzolaro,

Affiliations Department of Pharmacy-Drug-Science, University of Bari, Bari, Italy, Centro de Neurociencias de Valparaíso, Facultad de Ciencias, Universidad de Valparaiso, Valparaíso, Chile
⨯
Gianluigi Cannone,

Affiliations Department of Pharmacy-Drug-Science, University of Bari, Bari, Italy, Centro de Neurociencias de Valparaíso, Facultad de Ciencias, Universidad de Valparaiso, Valparaíso, Chile
⨯
Giulia Maria Camerino,

Affiliations Department of Pharmacy-Drug-Science, University of Bari, Bari, Italy, Centro de Neurociencias de Valparaíso, Facultad de Ciencias, Universidad de Valparaiso, Valparaíso, Chile
⨯
Maria Maddalena Dinardo,

Affiliations Department of Pharmacy-Drug-Science, University of Bari, Bari, Italy, Centro de Neurociencias de Valparaíso, Facultad de Ciencias, Universidad de Valparaiso, Valparaíso, Chile
⨯
Ramon Latorre,

Affiliations Department of Pharmacy-Drug-Science, University of Bari, Bari, Italy, Centro de Neurociencias de Valparaíso, Facultad de Ciencias, Universidad de Valparaiso, Valparaíso, Chile
⨯
Diana Conte Camerino

Affiliations Department of Pharmacy-Drug-Science, University of Bari, Bari, Italy, Centro de Neurociencias de Valparaíso, Facultad de Ciencias, Universidad de Valparaiso, Valparaíso, Chile
⨯

Emerging Role of Calcium-Activated Potassium Channel in the Regulation of Cell Viability Following Potassium Ions Challenge in HEK293 Cells and Pharmacological Modulation

Domenico Tricarico,
Antonietta Mele,
Sara Calzolaro,
Gianluigi Cannone,
Giulia Maria Camerino,
Maria Maddalena Dinardo,
Ramon Latorre,
Diana Conte Camerino

Published: July 16, 2013
https://doi.org/10.1371/journal.pone.0069551

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Membrane potential
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Drug therapy
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Paralysis
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Skeletal muscles
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Transfection
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Potassium
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