The Synthetic Amphipathic Peptidomimetic LTX109 Is a Potent Fungicide That Disturbs Plasma Membrane Integrity in a Sphingolipid Dependent Manner

Open Access

Peer-reviewed

Research Article

Rasmus Bojsen ,

Contributed equally to this work with: Rasmus Bojsen, Rasmus Torbensen

Affiliation Department of Systems Biology, Technical University of Denmark, Kgs. Lyngby, Denmark
⨯
Rasmus Torbensen ,

Contributed equally to this work with: Rasmus Bojsen, Rasmus Torbensen

Affiliation Department of Biology, University of Copenhagen, Copenhagen, Denmark
⨯
Camilla Eggert Larsen,

Affiliation Department of Biology, University of Copenhagen, Copenhagen, Denmark
⨯
Anders Folkesson,

Affiliations Department of Systems Biology, Technical University of Denmark, Kgs. Lyngby, Denmark, Section for Bacteriology, Pathology and Parasitology, National Veterinary Institute, Frederiksberg C, Denmark
⨯
Birgitte Regenberg

* E-mail: bregenberg@bio.ku.dk

Affiliation Department of Biology, University of Copenhagen, Copenhagen, Denmark
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Saccharomyces cerevisiae
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Sphingolipids
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Cell membranes
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Yeast
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Antifungals
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Amphotericin
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Bacterial biofilms
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Fungicides
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