Static Mechanical Stress Induces Apoptosis in Rat Endplate Chondrocytes through MAPK and Mitochondria-Dependent Caspase Activation Signaling Pathways

Open Access

Peer-reviewed

Research Article

Dechao Kong ,

Contributed equally to this work with: Dechao Kong, Tiansheng Zheng

Affiliation Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Tiansheng Zheng ,

Contributed equally to this work with: Dechao Kong, Tiansheng Zheng

Affiliation Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Ming Zhang,

Affiliation Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Daode Wang,

Affiliation Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Shihao Du,

Affiliation Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Xiang Li,

Affiliation Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Jiahu Fang ,

* E-mail: fjh4508@163.com (JF); xiaojiancao@gmail.com (XC)

Affiliation Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Xiaojian Cao

* E-mail: fjh4508@163.com (JF); xiaojiancao@gmail.com (XC)

Affiliation Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Apoptosis
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Chondrocytes
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Mechanical stress
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Mitochondria
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Statics
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MAPK signaling cascades
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Cell staining
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Protein kinase signaling cascade
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