Phage P1-Derived Artificial Chromosomes Facilitate Heterologous Expression of the FK506 Gene Cluster

• Adam C. Jones,

  Affiliation Pharmaceutical Institute, University of Tübingen, Tübingen, Germany

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• Bertolt Gust,

  Affiliation Pharmaceutical Institute, University of Tübingen, Tübingen, Germany

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• Andreas Kulik,

  Affiliation Department of Microbiology and Biotechnology, University of Tübingen, Tübingen, Germany

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• Lutz Heide,

  Affiliation Pharmaceutical Institute, University of Tübingen, Tübingen, Germany

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• Mark J. Buttner ,

  * E-mail: mark.buttner@jic.ac.uk (M. Buttner); mervyn.bibb@jic.ac.uk (M. Bibb)

  Affiliation Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich, United Kingdom

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• Mervyn J. Bibb

  * E-mail: mark.buttner@jic.ac.uk (M. Buttner); mervyn.bibb@jic.ac.uk (M. Bibb)

  Affiliation Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich, United Kingdom

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