Overexpressed DNA Polymerase Iota Regulated by JNK/c-Jun Contributes to Hypermutagenesis in Bladder Cancer

Open Access

Peer-reviewed

Research Article

Fang Yuan,

Affiliation Urology Institute of People Liberation Army, Southwest Hospital, The Third Military Medical University, Chongqing, China
⨯
Zhigang Xu,

Affiliation Urology Institute of People Liberation Army, Southwest Hospital, The Third Military Medical University, Chongqing, China
⨯
Mingzhen Yang,

Affiliation Department of Clinical Biochemistry, The Third Military Medical University, Chongqing, China
⨯
Quanfang Wei,

Affiliation Department of Cell Biology, The Third Military Medical University, Chongqing, China
⨯
Yi Zhang,

Affiliation Department of Cell Biology, The Third Military Medical University, Chongqing, China
⨯
Jin Yu,

Affiliation Department of Cell Biology, The Third Military Medical University, Chongqing, China
⨯
Yi Zhi,

Affiliation Urology Institute of People Liberation Army, Southwest Hospital, The Third Military Medical University, Chongqing, China
⨯
Yang Liu,

Affiliation Urology Institute of People Liberation Army, Southwest Hospital, The Third Military Medical University, Chongqing, China
⨯
Zhiwen Chen ,

* E-mail: zhiwen@tmmu.edu.cn (ZC); jinyang@tmmu.edu.cn (J. Yang)

Affiliation Urology Institute of People Liberation Army, Southwest Hospital, The Third Military Medical University, Chongqing, China
⨯
Jin Yang

* E-mail: zhiwen@tmmu.edu.cn (ZC); jinyang@tmmu.edu.cn (J. Yang)

Affiliation Department of Cell Biology, The Third Military Medical University, Chongqing, China
⨯

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Bladder cancer
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DNA damage
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Cancer treatment
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c-Jun N-terminal kinase signaling cascade
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MAPK signaling cascades
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Mutation
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Point mutation
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Bladder
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