The Severity of Osteogenesis Imperfecta and Type I Collagen Pattern in Human Skin as Determined by Nonlinear Microscopy: Proof of Principle of a Diagnostic Method

• Javier Adur ,

  Contributed equally to this work with: Javier Adur, Lilia DSouza-Li

  * E-mail: jadur@bioingenieria.edu.ar

  Affiliations Biophotonic Group, Optics and Photonics Research Center (CEPOF), Institute of Physics “Gleb Wataghin,” State University of Campinas – UNICAMP, Campinas, São Paulo, Brazil, Microscopy Laboratory Applied to Molecular and Cellular Studies, School of Bioengineering, National University of Entre Ríos, Oro Verde, Entre Ríos, Argentina

  ⨯
• Lilia DSouza-Li ,

  Contributed equally to this work with: Javier Adur, Lilia DSouza-Li

  Affiliation Pediatric Endocrinology Laboratory, CIPED, State University of Campinas - UNICAMP, Campinas, São Paulo, Brazil

  ⨯
• Marcus Vinícius Pedroni,

  Affiliation Pediatric Endocrinology Laboratory, CIPED, State University of Campinas - UNICAMP, Campinas, São Paulo, Brazil

  ⨯
• Carlos E. Steiner,

  Affiliation Department of Medical Genetics, Faculty of Medical Science, State University of Campinas – UNICAMP, Campinas, São Paulo, Brazil

  ⨯
• Vitor B. Pelegati,

  Affiliation INFABiC - National Institute of Science and Technology on Photonics Applied to Cell Biology, Campinas, São Paulo, Brazil

  ⨯
• Andre A. de Thomaz,

  Affiliation Biophotonic Group, Optics and Photonics Research Center (CEPOF), Institute of Physics “Gleb Wataghin,” State University of Campinas – UNICAMP, Campinas, São Paulo, Brazil

  ⨯
• Hernandes F. Carvalho,

  Affiliations INFABiC - National Institute of Science and Technology on Photonics Applied to Cell Biology, Campinas, São Paulo, Brazil, Department of Structural and Functional Biology, Institute of Biology, State University of Campinas – UNICAMP, Campinas, São Paulo, Brazil

  ⨯
• Carlos L. Cesar

  Affiliations Biophotonic Group, Optics and Photonics Research Center (CEPOF), Institute of Physics “Gleb Wataghin,” State University of Campinas – UNICAMP, Campinas, São Paulo, Brazil, INFABiC - National Institute of Science and Technology on Photonics Applied to Cell Biology, Campinas, São Paulo, Brazil

  ⨯