Hypoxia Modulates Fibroblastic Architecture, Adhesion and Migration: A Role for HIF-1α in Cofilin Regulation and Cytoplasmic Actin Distribution

Melanie Vogler; Sabine Vogel; Sabine Krull; Katja Farhat; Pia Leisering; Susanne Lutz; Christina M. Wuertz; Dörthe M. Katschinski; Anke Zieseniss

doi:10.1371/journal.pone.0069128

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Peer-reviewed

Research Article

Hypoxia Modulates Fibroblastic Architecture, Adhesion and Migration: A Role for HIF-1α in Cofilin Regulation and Cytoplasmic Actin Distribution

Melanie Vogler ,

Contributed equally to this work with: Melanie Vogler, Sabine Vogel

Affiliation Institute of Cardiovascular Physiology, University Medical Center, Georg-August-University Goettingen, Goettingen, Germany
⨯
Sabine Vogel ,

Contributed equally to this work with: Melanie Vogler, Sabine Vogel

Affiliation Institute of Cardiovascular Physiology, University Medical Center, Georg-August-University Goettingen, Goettingen, Germany
⨯
Sabine Krull,

Affiliation Institute of Cardiovascular Physiology, University Medical Center, Georg-August-University Goettingen, Goettingen, Germany
⨯
Katja Farhat,

Affiliation Institute of Cardiovascular Physiology, University Medical Center, Georg-August-University Goettingen, Goettingen, Germany
⨯
Pia Leisering,

Affiliation Institute of Cardiovascular Physiology, University Medical Center, Georg-August-University Goettingen, Goettingen, Germany
⨯
Susanne Lutz,

Affiliation Institute of Pharmacology, University Medical Center, Georg-August-University Goettingen, Goettingen, Germany
⨯
Christina M. Wuertz,

Affiliation Institute of Pharmacology, University Medical Center, Georg-August-University Goettingen, Goettingen, Germany
⨯
Dörthe M. Katschinski,

Affiliation Institute of Cardiovascular Physiology, University Medical Center, Georg-August-University Goettingen, Goettingen, Germany
⨯
Anke Zieseniss

* E-mail: anke.zieseniss@med.uni-goettingen.de

Affiliation Institute of Cardiovascular Physiology, University Medical Center, Georg-August-University Goettingen, Goettingen, Germany
⨯

Hypoxia Modulates Fibroblastic Architecture, Adhesion and Migration: A Role for HIF-1α in Cofilin Regulation and Cytoplasmic Actin Distribution

Melanie Vogler,
Sabine Vogel,
Sabine Krull,
Katja Farhat,
Pia Leisering,
Susanne Lutz,
Christina M. Wuertz,
Dörthe M. Katschinski,
Anke Zieseniss

Published: July 18, 2013
https://doi.org/10.1371/journal.pone.0069128

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Hypoxia
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Medical hypoxia
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Actins
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L929 cells
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Cloning
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Fibroblasts
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Cell migration
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Cytoskeleton
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