Identification of a Lifespan Extending Mutation in the Schizosaccharomyces pombe Cyclin Gene clg1⁺ by Direct Selection of Long-Lived Mutants

• Bo-Ruei Chen,

  Current address: Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA

  Affiliations Department of Molecular Genetics, Cleveland Clinic Lerner College of Medicine at Case Western Reserve University, Cleveland, Ohio, USA, Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America, Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America

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• Yanhui Li,

  Affiliations Department of Molecular Genetics, Cleveland Clinic Lerner College of Medicine at Case Western Reserve University, Cleveland, Ohio, USA, Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America

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• Jessica R. Eisenstatt,

  Current address: Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA

  Affiliations Department of Molecular Genetics, Cleveland Clinic Lerner College of Medicine at Case Western Reserve University, Cleveland, Ohio, USA, Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America

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• Kurt W. Runge

  * E-mail: rungek@ccf.org

  Affiliations Department of Molecular Genetics, Cleveland Clinic Lerner College of Medicine at Case Western Reserve University, Cleveland, Ohio, USA, Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America

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