Activation of AMPK Inhibits Cholera Toxin Stimulated Chloride Secretion in Human and Murine Intestine

Ailín C. Rogers; Lisa Huetter; Nadia Hoekstra; Danielle Collins; Anne Collaco; Alan W. Baird; Desmond C. Winter; Nadia Ameen; John P. Geibel; Sascha Kopic

doi:10.1371/journal.pone.0069050

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Peer-reviewed

Research Article

Activation of AMPK Inhibits Cholera Toxin Stimulated Chloride Secretion in Human and Murine Intestine

Ailín C. Rogers ,

Contributed equally to this work with: Ailín C. Rogers, Lisa Huetter

Affiliation University College Dublin and St. Vincent's University Hospital, Dublin, Ireland
⨯
Lisa Huetter ,

Contributed equally to this work with: Ailín C. Rogers, Lisa Huetter

Affiliations Institute of Physiology and Pathophysiology, Paracelsus Medical University, Salzburg, Austria, Department of Surgery, Yale University, School of Medicine, New Haven, Connecticut, United States of America
⨯
Nadia Hoekstra,

Affiliation Department of Pediatrics, Yale University, School of Medicine, New Haven, Connecticut, United States of America
⨯
Danielle Collins,

Affiliation University College Dublin and St. Vincent's University Hospital, Dublin, Ireland
⨯
Anne Collaco,

Affiliation Department of Pediatrics, Yale University, School of Medicine, New Haven, Connecticut, United States of America
⨯
Alan W. Baird,

Affiliation University College Dublin and St. Vincent's University Hospital, Dublin, Ireland
⨯
Desmond C. Winter,

Affiliation University College Dublin and St. Vincent's University Hospital, Dublin, Ireland
⨯
Nadia Ameen,

Affiliations Department of Pediatrics, Yale University, School of Medicine, New Haven, Connecticut, United States of America, Department of Cellular and Molecular Physiology, Yale University, School of Medicine, New Haven, Connecticut, United States of America
⨯
John P. Geibel,

Affiliations Department of Surgery, Yale University, School of Medicine, New Haven, Connecticut, United States of America, Department of Cellular and Molecular Physiology, Yale University, School of Medicine, New Haven, Connecticut, United States of America
⨯
Sascha Kopic

* E-mail: sascha.kopic@gmail.com

Affiliations Department of Surgery, Yale University, School of Medicine, New Haven, Connecticut, United States of America, Department of Cellular and Molecular Physiology, Yale University, School of Medicine, New Haven, Connecticut, United States of America
⨯

Activation of AMPK Inhibits Cholera Toxin Stimulated Chloride Secretion in Human and Murine Intestine

Ailín C. Rogers,
Lisa Huetter,
Nadia Hoekstra,
Danielle Collins,
Anne Collaco,
Alan W. Baird,
Desmond C. Winter,
Nadia Ameen,
John P. Geibel,
Sascha Kopic

Published: July 30, 2013
https://doi.org/10.1371/journal.pone.0069050

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Chlorides
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Gastrointestinal tract
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Colon
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Cholera
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