WT1 Promotes Cell Proliferation in Non-Small Cell Lung Cancer Cell Lines through Up-Regulating Cyclin D1 and p-pRb In Vitro and In Vivo

Caihua Xu; Chen Wu; Yang Xia; Zhaopeng Zhong; Xiang Liu; Jing Xu; Fei Cui; Bin Chen; Oluf Dimitri Røe; Aihong Li; Yijiang Chen

doi:10.1371/journal.pone.0068837

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Open Access

Peer-reviewed

Research Article

WT1 Promotes Cell Proliferation in Non-Small Cell Lung Cancer Cell Lines through Up-Regulating Cyclin D1 and p-pRb In Vitro and In Vivo

Caihua Xu ,

Contributed equally to this work with: Caihua Xu, Chen Wu

Affiliation Department of Cardiovascular Surgery, The First Affiliated Hospital of Soochow University, Soochow, Jiangsu, China
⨯
Chen Wu ,

Contributed equally to this work with: Caihua Xu, Chen Wu

Affiliation Department of Thoracic and Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
⨯
Yang Xia,

Affiliation Department of Thoracic and Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
⨯
Zhaopeng Zhong,

Affiliation Department of Thoracic and Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
⨯
Xiang Liu,

Affiliation Department of Thoracic and Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
⨯
Jing Xu,

Affiliation Department of Thoracic and Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
⨯
Fei Cui,

Affiliation Department of Thoracic and Cardiovascular Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China
⨯
Bin Chen,

Affiliation Department of Thoracic and Cardiovascular Surgery, Wuxi NO.2 People’s Hospital, Wuxi, Jiangsu, China
⨯
Oluf Dimitri Røe,

Affiliation Department of Cancer Research and Molecular Medicine (IKM), Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway
⨯
Aihong Li,

Affiliation Department of Medical Biosciences, Clinic chemistry, Umea University, Umea, Sweden
⨯
Yijiang Chen

* E-mail: YJChen@NJMU.edu.cn

Affiliation Department of Thoracic and Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
⨯

WT1 Promotes Cell Proliferation in Non-Small Cell Lung Cancer Cell Lines through Up-Regulating Cyclin D1 and p-pRb In Vitro and In Vivo

Caihua Xu,
Chen Wu,
Yang Xia,
Zhaopeng Zhong,
Xiang Liu,
Jing Xu,
Fei Cui,
Bin Chen,
Oluf Dimitri Røe,
Aihong Li

Published: August 1, 2013
https://doi.org/10.1371/journal.pone.0068837

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Non-small cell lung cancer
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Cyclins
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Cancers and neoplasms
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