Identification of a Novel Sulfonamide Non-Nucleoside Reverse Transcriptase Inhibitor by a Phenotypic HIV-1 Full Replication Assay

Tae-Hee Kim; Yoonae Ko; Thierry Christophe; Jonathan Cechetto; Junwon Kim; Kyoung-Ae Kim; Annette S. Boese; Jean-Michel Garcia; Denis Fenistein; Moon Kyeong Ju; Junghwan Kim; Sung-Jun Han; Ho Jeong Kwon; Vincent Brondani; Peter Sommer

doi:10.1371/journal.pone.0068767

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Open Access

Peer-reviewed

Research Article

Identification of a Novel Sulfonamide Non-Nucleoside Reverse Transcriptase Inhibitor by a Phenotypic HIV-1 Full Replication Assay

Tae-Hee Kim,

Affiliations Institut Pasteur Korea, Seongnam-Si, Gyeonggi-Do, Korea, Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea
⨯
Yoonae Ko,

Affiliation Institut Pasteur Korea, Seongnam-Si, Gyeonggi-Do, Korea
⨯
Thierry Christophe,

Affiliation Institut Pasteur Korea, Seongnam-Si, Gyeonggi-Do, Korea
⨯
Jonathan Cechetto,

Affiliation Institut Pasteur Korea, Seongnam-Si, Gyeonggi-Do, Korea
⨯
Junwon Kim,

Affiliation Institut Pasteur Korea, Seongnam-Si, Gyeonggi-Do, Korea
⨯
Kyoung-Ae Kim,

Affiliation Institut Pasteur Korea, Seongnam-Si, Gyeonggi-Do, Korea
⨯
Annette S. Boese,

Affiliation Institut Pasteur Korea, Seongnam-Si, Gyeonggi-Do, Korea
⨯
Jean-Michel Garcia,

Affiliation Institut Pasteur Korea, Seongnam-Si, Gyeonggi-Do, Korea
⨯
Denis Fenistein,

Affiliation Institut Pasteur Korea, Seongnam-Si, Gyeonggi-Do, Korea
⨯
Moon Kyeong Ju,

Affiliation Institut Pasteur Korea, Seongnam-Si, Gyeonggi-Do, Korea
⨯
Junghwan Kim,

Affiliation Institut Pasteur Korea, Seongnam-Si, Gyeonggi-Do, Korea
⨯
Sung-Jun Han,

Affiliation Institut Pasteur Korea, Seongnam-Si, Gyeonggi-Do, Korea
⨯
Ho Jeong Kwon ,

* E-mail: peter@ip-korea.org (PS); kwonhj@yonsei.ac.kr (HK)

Affiliation Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea
⨯
Vincent Brondani ,

Contributed equally to this work with: Vincent Brondani, Peter Sommer

Affiliation Institut Pasteur Korea, Seongnam-Si, Gyeonggi-Do, Korea
⨯
Peter Sommer

Contributed equally to this work with: Vincent Brondani, Peter Sommer

* E-mail: peter@ip-korea.org (PS); kwonhj@yonsei.ac.kr (HK)

Affiliation Institut Pasteur Korea, Seongnam-Si, Gyeonggi-Do, Korea
⨯

Identification of a Novel Sulfonamide Non-Nucleoside Reverse Transcriptase Inhibitor by a Phenotypic HIV-1 Full Replication Assay

Tae-Hee Kim,
Yoonae Ko,
Thierry Christophe,
Jonathan Cechetto,
Junwon Kim,
Kyoung-Ae Kim,
Annette S. Boese,
Jean-Michel Garcia,
Denis Fenistein,
Moon Kyeong Ju

Published: July 18, 2013
https://doi.org/10.1371/journal.pone.0068767

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