An Inducible Transgenic Mouse Model for Immune Mediated Hepatitis Showing Clearance of Antigen Expressing Hepatocytes by CD8+ T Cells

Open Access

Peer-reviewed

Research Article

Marcin Cebula,

Affiliation Model Systems for Infection and Immunity, Helmholtz Centre for Infection Research, Braunschweig, Germany
⨯
Aaron Ochel,

Affiliation Model Systems for Infection and Immunity, Helmholtz Centre for Infection Research, Braunschweig, Germany
⨯
Upneet Hillebrand,

Affiliation Model Systems for Infection and Immunity, Helmholtz Centre for Infection Research, Braunschweig, Germany
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Marina C. Pils,

Affiliation Mouse Pathology, Helmholtz Centre for Infection Research, Braunschweig, Germany
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Reinhold Schirmbeck,

Affiliation Internal medicine I, University Hospital Ulm, Ulm, Germany
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Hansjörg Hauser,

Affiliation Gene Regulation and Differentiation, Helmholtz Centre for Infection Research, Braunschweig, Germany
⨯
Dagmar Wirth

* E-mail: Dagmar.wirth@helmholtz-hzi.de

Affiliation Model Systems for Infection and Immunity, Helmholtz Centre for Infection Research, Braunschweig, Germany
⨯

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T cells
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Hepatocytes
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Mouse models
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Genetically modified animals
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Immune response
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Cytotoxic T cells
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Hepatitis
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Adoptive transfer
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