High Levels of S100A8/A9 Proteins Aggravate Ventilator-Induced Lung Injury via TLR4 Signaling

• Maria T. Kuipers ,

  Contributed equally to this work with: Maria T. Kuipers, Thomas Vogl

  * E-mail: Ilse.Kuipers@amc.nl

  Affiliations Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, Amsterdam, The Netherlands, Center of Experimental and Molecular Medicine, Academic Medical Center, Amsterdam, The Netherlands

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• Thomas Vogl ,

  Contributed equally to this work with: Maria T. Kuipers, Thomas Vogl

  Affiliations Institute of Immunology, University of Münster, Münster, Germany, Interdisciplinary Center of Clinical Research, University of Münster, Münster, Germany

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• Hamid Aslami,

  Affiliation Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, Amsterdam, The Netherlands

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• Geartsje Jongsma,

  Affiliation Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, Amsterdam, The Netherlands

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• Elske van den Berg,

  Affiliation Pediatric Intensive Care Unit, Emma Children’s Hospital Academic Medical Center, Amsterdam, The Netherlands

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• Alexander P. J. Vlaar,

  Affiliation Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, Amsterdam, The Netherlands

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• Joris J. T. H. Roelofs,

  Affiliation Department of Pathology, Academic Medical Center, Amsterdam, The Netherlands

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• Nicole P. Juffermans,

  Affiliations Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, Amsterdam, The Netherlands, Department of Intensive Care, Academic Medical Center, Amsterdam, The Netherlands

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• Marcus J. Schultz,

  Affiliations Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, Amsterdam, The Netherlands, Department of Intensive Care, Academic Medical Center, Amsterdam, The Netherlands

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• Tom van der Poll,

  Affiliations Center of Experimental and Molecular Medicine, Academic Medical Center, Amsterdam, The Netherlands, Center of Infection and Immunity, Academic Medical Center, Amsterdam, The Netherlands

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• Johannes Roth,

  Affiliations Institute of Immunology, University of Münster, Münster, Germany, Interdisciplinary Center of Clinical Research, University of Münster, Münster, Germany

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• Catharina W. Wieland

  Affiliation Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, Amsterdam, The Netherlands

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