Microbial Products Induce Claudin-2 to Compromise Gut Epithelial Barrier Function

Xiaoyu Liu; Gui Yang; Xiao-Rui Geng; Yanjuan Cao; Na Li; Li Ma; Si Chen; Ping-Chang Yang; Zhigang Liu

doi:10.1371/journal.pone.0068547

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Open Access

Peer-reviewed

Research Article

Microbial Products Induce Claudin-2 to Compromise Gut Epithelial Barrier Function

Xiaoyu Liu ,

Contributed equally to this work with: Xiaoyu Liu, Gui Yang, Xiao-Rui Geng

Affiliation State Key Laboratory of Respiratory Disease for Allergy at Shenzhen University, Shenzhen Key Laboratory of Allergy & Immunology, Shenzhen University School of Medicine, Shenzhen, China
⨯
Gui Yang ,

Contributed equally to this work with: Xiaoyu Liu, Gui Yang, Xiao-Rui Geng

Affiliation Longgang Central Hospital, ENT Hospital, Shenzhen ENT Institute, Shenzhen, China
⨯
Xiao-Rui Geng ,

Contributed equally to this work with: Xiaoyu Liu, Gui Yang, Xiao-Rui Geng

Affiliation Longgang Central Hospital, ENT Hospital, Shenzhen ENT Institute, Shenzhen, China
⨯
Yanjuan Cao,

Affiliation State Key Laboratory of Respiratory Disease for Allergy at Shenzhen University, Shenzhen Key Laboratory of Allergy & Immunology, Shenzhen University School of Medicine, Shenzhen, China
⨯
Na Li,

Affiliation State Key Laboratory of Respiratory Disease for Allergy at Shenzhen University, Shenzhen Key Laboratory of Allergy & Immunology, Shenzhen University School of Medicine, Shenzhen, China
⨯
Li Ma,

Affiliation State Key Laboratory of Respiratory Disease for Allergy at Shenzhen University, Shenzhen Key Laboratory of Allergy & Immunology, Shenzhen University School of Medicine, Shenzhen, China
⨯
Si Chen,

Affiliation State Key Laboratory of Respiratory Disease for Allergy at Shenzhen University, Shenzhen Key Laboratory of Allergy & Immunology, Shenzhen University School of Medicine, Shenzhen, China
⨯
Ping-Chang Yang,

Affiliation State Key Laboratory of Respiratory Disease for Allergy at Shenzhen University, Shenzhen Key Laboratory of Allergy & Immunology, Shenzhen University School of Medicine, Shenzhen, China
⨯
Zhigang Liu

* E-mail: zhigangliu195910@126.com

Affiliation State Key Laboratory of Respiratory Disease for Allergy at Shenzhen University, Shenzhen Key Laboratory of Allergy & Immunology, Shenzhen University School of Medicine, Shenzhen, China
⨯

Microbial Products Induce Claudin-2 to Compromise Gut Epithelial Barrier Function

Xiaoyu Liu,
Gui Yang,
Xiao-Rui Geng,
Yanjuan Cao,
Na Li,
Li Ma,
Si Chen,
Ping-Chang Yang,
Zhigang Liu

Published: August 21, 2013
https://doi.org/10.1371/journal.pone.0068547

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