Is It Possible to Improve Memory Function by Upregulation of the Cholesterol 24S-Hydroxylase (CYP46A1) in the Brain?

Silvia Maioli; Ann Båvner; Zeina Ali; Maura Heverin; Muhammad-Al-Mustafa Ismail; Elena Puerta; Maria Olin; Ahmed Saeed; Marjan Shafaati; Paolo Parini; Angel Cedazo-Minguez; Ingemar Björkhem

doi:10.1371/journal.pone.0068534

Loading metrics

Open Access

Peer-reviewed

Research Article

Is It Possible to Improve Memory Function by Upregulation of the Cholesterol 24S-Hydroxylase (CYP46A1) in the Brain?

Silvia Maioli ,

Contributed equally to this work with: Silvia Maioli, Ann Båvner

* E-mail: silvia.maioli@ki.se

Affiliation Department of Neurobiology, Care Sciences and Society, Karolinska Institutet-Alzheimer’s Disease Research Center, Novum, Stockholm, Sweden
⨯
Ann Båvner ,

Contributed equally to this work with: Silvia Maioli, Ann Båvner

Affiliation Department of Laboratory Medicine, Division of Clinical Chemistry, Karolinska Institutet, Karolinska University Hospital, Huddinge, Sweden
⨯
Zeina Ali,

Affiliation Department of Laboratory Medicine, Division of Clinical Chemistry, Karolinska Institutet, Karolinska University Hospital, Huddinge, Sweden
⨯
Maura Heverin,

Affiliation Department of Laboratory Medicine, Division of Clinical Chemistry, Karolinska Institutet, Karolinska University Hospital, Huddinge, Sweden
⨯
Muhammad-Al-Mustafa Ismail,

Affiliation Department of Neurobiology, Care Sciences and Society, Karolinska Institutet-Alzheimer’s Disease Research Center, Novum, Stockholm, Sweden
⨯
Elena Puerta,

Affiliation Department of Neurobiology, Care Sciences and Society, Karolinska Institutet-Alzheimer’s Disease Research Center, Novum, Stockholm, Sweden
⨯
Maria Olin,

Affiliation Department of Laboratory Medicine, Division of Clinical Chemistry, Karolinska Institutet, Karolinska University Hospital, Huddinge, Sweden
⨯
Ahmed Saeed,

Affiliation Department of Laboratory Medicine, Division of Clinical Chemistry, Karolinska Institutet, Karolinska University Hospital, Huddinge, Sweden
⨯
Marjan Shafaati,

Affiliation Department of Laboratory Medicine, Division of Clinical Chemistry, Karolinska Institutet, Karolinska University Hospital, Huddinge, Sweden
⨯
Paolo Parini,

Affiliation Department of Laboratory Medicine, Division of Clinical Chemistry, Karolinska Institutet, Karolinska University Hospital, Huddinge, Sweden
⨯
Angel Cedazo-Minguez,

Affiliation Department of Neurobiology, Care Sciences and Society, Karolinska Institutet-Alzheimer’s Disease Research Center, Novum, Stockholm, Sweden
⨯
Ingemar Björkhem

Affiliation Department of Laboratory Medicine, Division of Clinical Chemistry, Karolinska Institutet, Karolinska University Hospital, Huddinge, Sweden
⨯

Is It Possible to Improve Memory Function by Upregulation of the Cholesterol 24S-Hydroxylase (CYP46A1) in the Brain?

Silvia Maioli,
Ann Båvner,
Zeina Ali,
Maura Heverin,
Muhammad-Al-Mustafa Ismail,
Elena Puerta,
Maria Olin,
Ahmed Saeed,
Marjan Shafaati,
Paolo Parini

Published: July 16, 2013
https://doi.org/10.1371/journal.pone.0068534

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Cholesterol
Is the Subject Area "Cholesterol" applicable to this article?

Thanks for your feedback.
Homozygosity
Is the Subject Area "Homozygosity" applicable to this article?

Thanks for your feedback.
Heterozygosity
Is the Subject Area "Heterozygosity" applicable to this article?

Thanks for your feedback.
Hippocampus
Is the Subject Area "Hippocampus" applicable to this article?

Thanks for your feedback.
Memory
Is the Subject Area "Memory" applicable to this article?

Thanks for your feedback.
Spatial memory
Is the Subject Area "Spatial memory" applicable to this article?

Thanks for your feedback.
Hyperexpression techniques
Is the Subject Area "Hyperexpression techniques" applicable to this article?

Thanks for your feedback.