Henryin, an ent-kaurane Diterpenoid, Inhibits Wnt Signaling through Interference with β-Catenin/TCF4 Interaction in Colorectal Cancer Cells

Xingyao Li; Jianxin Pu; Shiyou Jiang; Jia Su; Lingmei Kong; Bingyu Mao; Handong Sun; Yan Li

doi:10.1371/journal.pone.0068525

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Peer-reviewed

Research Article

Henryin, an ent-kaurane Diterpenoid, Inhibits Wnt Signaling through Interference with β-Catenin/TCF4 Interaction in Colorectal Cancer Cells

Xingyao Li,

Affiliations State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China, University of the Chinese Academy of Sciences, Beijing, China
⨯
Jianxin Pu,

Affiliation State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China
⨯
Shiyou Jiang,

Affiliations State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China, University of the Chinese Academy of Sciences, Beijing, China
⨯
Jia Su,

Affiliations State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China, University of the Chinese Academy of Sciences, Beijing, China
⨯
Lingmei Kong,

Affiliations State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China, University of the Chinese Academy of Sciences, Beijing, China
⨯
Bingyu Mao,

Affiliation State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
⨯
Handong Sun ,

* E-mail: liyanb@mail.kib.ac.cn (YL); hdsun@mail.kib.ac.cn (HS)

Affiliation State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China
⨯
Yan Li

* E-mail: liyanb@mail.kib.ac.cn (YL); hdsun@mail.kib.ac.cn (HS)

Affiliation State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China
⨯

Henryin, an ent-kaurane Diterpenoid, Inhibits Wnt Signaling through Interference with β-Catenin/TCF4 Interaction in Colorectal Cancer Cells

Xingyao Li,
Jianxin Pu,
Shiyou Jiang,
Jia Su,
Lingmei Kong,
Bingyu Mao,
Handong Sun,
Yan Li

Published: July 2, 2013
https://doi.org/10.1371/journal.pone.0068525

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Wnt signaling cascade
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